STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuEExporter of leucine. Can also transport its natural analog L- alpha-amino-n-butyric acid and some other structurally unrelated amino acids (212 aa)    
Predicted Functional Partners:
ytfF
Inner membrane protein YtfF; Putative transmembrane subunit
      
 0.877
rhtA
Involved in the efflux of threonine and homoserine. Can also export other amino acids such as proline, serine, histidine and cysteine
   
  
 0.863
alaE
Exports L-alanine
      
 0.830
ydjY
annotation not available
      
 0.821
yoaG
annotation not available
 
   
 0.820
yddG
Probable efflux pump. Overexpression confers resistance to phenylalanine and increases export of phenylalanine, tyrosine and tryptophan
      
 0.813
yeaQ
annotation not available
     
 0.772
yeaR
Uncharacterized protein YeaR; Protein involved in xenobiotic metabolic process
     
 0.734
ydiH
annotation not available
  
   
 0.681
eamB
Exporter of O-acetylserine (OAS) and cysteine.
  
   
 0.655
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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