STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yoaBPutative reactive intermediate deaminase; RutC family protein YoaB; Putative enzyme; Not classified; Belongs to the RutC family (114 aa)    
Predicted Functional Partners:
yjgH
RutC family protein YjgH; Protein involved in translation
      
 0.785
ycaM
Inner membrane transporter YcaM; Putative transport; Not classified
   
  
 0.783
tdcF
2-iminobutanoate/2-iminopropanoate deaminase; May be a post-translational regulator that controls the metabolic fate of L-threonine or the potentially toxic intermediate 2- ketobutyrate
 
  
 0.755
rutC
Putative aminoacrylate deaminase, reactive intermediate detoxification; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce in vivo, but not in vitro in the pyrimidine nitrogen degradation
      
 0.731
yieK
Putative glucosamine-6-phosphate deaminase yiek; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family
      
 0.731
ridA
Enamine/imine deaminase, reaction intermediate detoxification; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities. Involved in the isoleucine biosynthesis (By similarity)
 
  
 0.722
yciI
annotation not available
   
  
 0.676
ynfA
annotation not available
      
 0.630
yciN
annotation not available
   
  
 0.628
ydcY
annotation not available
   
  
 0.625
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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