node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
mgrB | yebO | b1826 | b1825 | Regulatory peptide for PhoPQ, feedback inhibition; Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP. PhoP-regulated transcription is redox- sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway; the 2 periplasmic Cys residues of MgrB are required for its action on PhoQ, and thus PhoP. | Putative inner membrane protein. | 0.884 |
mgrB | yobF | b1826 | b1824 | Regulatory peptide for PhoPQ, feedback inhibition; Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP. PhoP-regulated transcription is redox- sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway; the 2 periplasmic Cys residues of MgrB are required for its action on PhoQ, and thus PhoP. | DUF2527 family heat-induced protein. | 0.515 |
mgrB | yobH | b1826 | b4536 | Regulatory peptide for PhoPQ, feedback inhibition; Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP. PhoP-regulated transcription is redox- sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway; the 2 periplasmic Cys residues of MgrB are required for its action on PhoQ, and thus PhoP. | Uncharacterized protein. | 0.692 |
sieB | yebO | b1353 | b1825 | Phage superinfection exclusion protein. | Putative inner membrane protein. | 0.446 |
sieB | yobF | b1353 | b1824 | Phage superinfection exclusion protein. | DUF2527 family heat-induced protein. | 0.533 |
yacL | yebO | b0119 | b1825 | UPF0231 family protein. | Putative inner membrane protein. | 0.510 |
yacL | yhfK | b0119 | b3358 | UPF0231 family protein. | Putative transporter, FUSC superfamily inner membrane protein; Protein involved in metabolic process. | 0.716 |
yceO | yebO | b1058 | b1825 | Uncharacterized protein. | Putative inner membrane protein. | 0.507 |
yceO | yobF | b1058 | b1824 | Uncharacterized protein. | DUF2527 family heat-induced protein. | 0.625 |
yebO | mgrB | b1825 | b1826 | Putative inner membrane protein. | Regulatory peptide for PhoPQ, feedback inhibition; Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP. PhoP-regulated transcription is redox- sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway; the 2 periplasmic Cys residues of MgrB are required for its action on PhoQ, and thus PhoP. | 0.884 |
yebO | sieB | b1825 | b1353 | Putative inner membrane protein. | Phage superinfection exclusion protein. | 0.446 |
yebO | yacL | b1825 | b0119 | Putative inner membrane protein. | UPF0231 family protein. | 0.510 |
yebO | yceO | b1825 | b1058 | Putative inner membrane protein. | Uncharacterized protein. | 0.507 |
yebO | yhfK | b1825 | b3358 | Putative inner membrane protein. | Putative transporter, FUSC superfamily inner membrane protein; Protein involved in metabolic process. | 0.539 |
yebO | yhiI | b1825 | b3487 | Putative inner membrane protein. | Putative membrane fusion protein (MFP) of efflux pump; Putative membrane protein. | 0.454 |
yebO | yobF | b1825 | b1824 | Putative inner membrane protein. | DUF2527 family heat-induced protein. | 0.469 |
yebO | yobH | b1825 | b4536 | Putative inner membrane protein. | Uncharacterized protein. | 0.715 |
yebO | ytfL | b1825 | b4218 | Putative inner membrane protein. | UPF0053 family inner membrane protein; Putative transport protein. | 0.529 |
yhfK | yacL | b3358 | b0119 | Putative transporter, FUSC superfamily inner membrane protein; Protein involved in metabolic process. | UPF0231 family protein. | 0.716 |
yhfK | yebO | b3358 | b1825 | Putative transporter, FUSC superfamily inner membrane protein; Protein involved in metabolic process. | Putative inner membrane protein. | 0.539 |