STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yebSIntermembrane transport protein yebs; Component of a transport pathway that contributes to membrane integrity (427 aa)    
Predicted Functional Partners:
yebT
Intermembrane transport protein yebt; Component of a transport pathway that contributes to membrane integrity . May directly span the intermembrane space, facilitating the transport of substrates across the periplasm (Probable)
  
 0.998
pqiB
Paraquat-inducible, soxrs-regulated mce domain protein; Paraquat-inducible protein B; Phenotype; Not classified; Belongs to the PqiB family
  
 0.973
rsmF
16S rRNA m(5)C1407 methyltransferase, SAM-dependent; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
      0.893
pqiC
Intermembrane transport lipoprotein pqic; Component of a transport pathway that contributes to membrane integrity
 
  
 0.891
mlaD
Phospholipid/cholesterol/gamma-hch transport system substrate-binding protein; Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane . MlaD functions in substrate binding with strong affinity for phospholipids and modulates ATP hydrolytic activity of the complex
 
   
 0.789
yjgN
annotation not available
      
 0.787
yecD
Isochorismatase family protein; Belongs to the isochorismatase family
      
 0.605
msrC
Free methionine-(r)-sulfoxide reductase; Catalyzes the reversible oxidation-reduction of the R- enantiomer of free methionine sulfoxide to methionine. Specific for free L-methionine-(R)-S-oxide
       0.585
mlaE
Abc transporter maintaining om lipid asymmetry, inner membrane permease protein; Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane
     
 0.537
mlaA
Intermembrane phospholipid transport system - outer membrane lipoprotein mlaa; Involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane
  
   
 0.536
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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