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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yebFannotation not available (118 aa)    
Predicted Functional Partners:
yebG
Dna damage-inducible protein regulated by lexa; Uncharacterized protein YebG; Protein involved in DNA repair and SOS response
 
  
 0.933
osmY
Salt-inducible putative abc transporter periplasmic binding protein; Hyperosmotically inducible periplasmic protein; Protein involved in response to osmotic stress
  
  
 0.694
yebE
annotation not available
  
 
 0.641
yegR
Uncharacterized protein YegR; Pseudogene, gpD phage P2-like protein D
      
 0.619
ypdI
annotation not available
      
 0.604
ogrK
Orphan ogr protein, positive regulator of p2 growth; Cryptic version of the phage P2 OGR protein which acts as an activator of P2 late transcription
      
 0.602
fliZ
Dna-binding transcriptional regulator fliz; During the post-exponential growth phase transiently interferes with RpoS (sigma S) activity without affecting expression of RpoS itself. It is probably not an anti-sigma factor as its overexpression is detrimental in rapidly growing cells where there is almost no sigma S factor. There is a strong overlap between Crl- activated genes and FliZ-down-regulated genes. FliZ acts as a timing device for expression of the genes for the adhesive curli fimbriae by indirectly decreasing expression of the curli regulator CsgD
  
     0.596
yjbJ
Stress-induced protein, upf0337 family; Belongs to the UPF0337 (CsbD) family
      
 0.593
yadE
Putative polysaccharide deacetylase lipoprotein; Uncharacterized protein YadE
      
 0.577
yeiH
annotation not available
      
 0.518
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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