STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yecDIsochorismatase family protein; Belongs to the isochorismatase family (188 aa)    
Predicted Functional Partners:
yecN
annotation not available
     
 0.941
yecE
DUF72 domain-containing protein YecE; Belongs to the UPF0759 family
  
  
 0.937
nnr
Adp-dependent nad(p)h-hydrate dehydratase / nad(p)h-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
  
    0.934
ycaC
Putative isochorismatase family hydrolase; Probable hydrolase YcaC; Protein involved in cellular amino acid catabolic process
      
 0.816
msbA
Atp-binding cassette, subfamily b, bacterial msba; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation
      
 0.731
cmoB
Trna (cmo5u34)-carboxymethyltransferase, carboxy-sam-dependent; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. Can also catalyze the SAM-dependent methylation of ho5U, with much lower efficiency
     
 0.713
nohD
Terminase small subunit / prophage dna-packing protein; DNA-packaging protein NU1 homolog; Bacteriophage DNA packaging protein
      
 0.605
yebS
Intermembrane transport protein yebs; Component of a transport pathway that contributes to membrane integrity
      
 0.605
cmoA
Carboxy-s-adenosyl-l-methionine synthase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)
       0.566
yccS
annotation not available
      
 0.561
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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