node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fecI | fecR | b4293 | b4292 | RNA polymerase sigma-19 factor, fec operon-specific; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates the fec genes for iron dicitrate transport (Probable); Belongs to the sigma-70 factor family. ECF subfamily. | Anti-sigma transmembrane signal transducer for ferric citrate transport; Regulation of iron dicitrate transport. In the absence of citrate FecR inactivates fecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm. | 0.999 |
fecI | yecH | b4293 | b1906 | RNA polymerase sigma-19 factor, fec operon-specific; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates the fec genes for iron dicitrate transport (Probable); Belongs to the sigma-70 factor family. ECF subfamily. | DUF2492 family protein. | 0.452 |
fecR | fecI | b4292 | b4293 | Anti-sigma transmembrane signal transducer for ferric citrate transport; Regulation of iron dicitrate transport. In the absence of citrate FecR inactivates fecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm. | RNA polymerase sigma-19 factor, fec operon-specific; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates the fec genes for iron dicitrate transport (Probable); Belongs to the sigma-70 factor family. ECF subfamily. | 0.999 |
fecR | yecH | b4292 | b1906 | Anti-sigma transmembrane signal transducer for ferric citrate transport; Regulation of iron dicitrate transport. In the absence of citrate FecR inactivates fecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm. | DUF2492 family protein. | 0.523 |
sgcA | sgcQ | b4302 | b4303 | Putative phosphotransferase enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. | Putative nucleoside triphosphatase; Belongs to the BtpA family. | 0.975 |
sgcA | sgcX | b4302 | b4305 | Putative phosphotransferase enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. | Putative endoglucanase with Zn-dependent exopeptidase domain; Putative lyase/synthase. | 0.972 |
sgcA | yecH | b4302 | b1906 | Putative phosphotransferase enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. | DUF2492 family protein. | 0.528 |
sgcQ | sgcA | b4303 | b4302 | Putative nucleoside triphosphatase; Belongs to the BtpA family. | Putative phosphotransferase enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. | 0.975 |
sgcQ | sgcX | b4303 | b4305 | Putative nucleoside triphosphatase; Belongs to the BtpA family. | Putative endoglucanase with Zn-dependent exopeptidase domain; Putative lyase/synthase. | 0.992 |
sgcQ | ydhI | b4303 | b1643 | Putative nucleoside triphosphatase; Belongs to the BtpA family. | DUF1656 family putative inner membrane efflux pump associated protein. | 0.451 |
sgcQ | yecH | b4303 | b1906 | Putative nucleoside triphosphatase; Belongs to the BtpA family. | DUF2492 family protein. | 0.757 |
sgcX | sgcA | b4305 | b4302 | Putative endoglucanase with Zn-dependent exopeptidase domain; Putative lyase/synthase. | Putative phosphotransferase enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. | 0.972 |
sgcX | sgcQ | b4305 | b4303 | Putative endoglucanase with Zn-dependent exopeptidase domain; Putative lyase/synthase. | Putative nucleoside triphosphatase; Belongs to the BtpA family. | 0.992 |
sgcX | slyA | b4305 | b1642 | Putative endoglucanase with Zn-dependent exopeptidase domain; Putative lyase/synthase. | Global transcriptional regulator; Transcription regulator that can specifically activate or repress expression of target genes. Activates expression of genes such as molecular chaperones (groL, groS, dnaK, grpE, and cbpA), proteins involved in acid resistance (hdeA, hdeB, and gadA), the starvation lipoprotein slp, virulence protein hlyE/clyA. Represses expression of genes involved in the histidine biosynthetic pathway such as hisA, hisB, hisD, hisF and hisG. Required for the activation of virulence genes; Belongs to the SlyA family. | 0.403 |
sgcX | ydhI | b4305 | b1643 | Putative endoglucanase with Zn-dependent exopeptidase domain; Putative lyase/synthase. | DUF1656 family putative inner membrane efflux pump associated protein. | 0.485 |
sgcX | yecH | b4305 | b1906 | Putative endoglucanase with Zn-dependent exopeptidase domain; Putative lyase/synthase. | DUF2492 family protein. | 0.757 |
slyA | sgcX | b1642 | b4305 | Global transcriptional regulator; Transcription regulator that can specifically activate or repress expression of target genes. Activates expression of genes such as molecular chaperones (groL, groS, dnaK, grpE, and cbpA), proteins involved in acid resistance (hdeA, hdeB, and gadA), the starvation lipoprotein slp, virulence protein hlyE/clyA. Represses expression of genes involved in the histidine biosynthetic pathway such as hisA, hisB, hisD, hisF and hisG. Required for the activation of virulence genes; Belongs to the SlyA family. | Putative endoglucanase with Zn-dependent exopeptidase domain; Putative lyase/synthase. | 0.403 |
slyA | ydhI | b1642 | b1643 | Global transcriptional regulator; Transcription regulator that can specifically activate or repress expression of target genes. Activates expression of genes such as molecular chaperones (groL, groS, dnaK, grpE, and cbpA), proteins involved in acid resistance (hdeA, hdeB, and gadA), the starvation lipoprotein slp, virulence protein hlyE/clyA. Represses expression of genes involved in the histidine biosynthetic pathway such as hisA, hisB, hisD, hisF and hisG. Required for the activation of virulence genes; Belongs to the SlyA family. | DUF1656 family putative inner membrane efflux pump associated protein. | 0.780 |
slyA | yecH | b1642 | b1906 | Global transcriptional regulator; Transcription regulator that can specifically activate or repress expression of target genes. Activates expression of genes such as molecular chaperones (groL, groS, dnaK, grpE, and cbpA), proteins involved in acid resistance (hdeA, hdeB, and gadA), the starvation lipoprotein slp, virulence protein hlyE/clyA. Represses expression of genes involved in the histidine biosynthetic pathway such as hisA, hisB, hisD, hisF and hisG. Required for the activation of virulence genes; Belongs to the SlyA family. | DUF2492 family protein. | 0.437 |
tyrP | yecH | b1907 | b1906 | Tyrosine transporter; Involved in transporting tyrosine across the cytoplasmic membrane. | DUF2492 family protein. | 0.500 |