STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliOFlagellar biosynthesis protein flio; Flagellar biosynthesis; Protein involved in flagellum assembly and taxis (121 aa)    
Predicted Functional Partners:
fliL
Flagellar biosynthesis protein; Controls the rotational direction of flagella during chemotaxis
 
 
 0.999
fliM
Flagellar motor switching and energizing component; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
 
  
 0.999
fliN
Flagellar motor switching and energizing component; FliN is one of three proteins (FliG, FliN, FliM) that form a switch complex that is proposed to be located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
 
  
 0.999
fliP
Flagellar biosynthesis protein flip; Plays a role in the flagellum-specific transport system
  
  
 0.999
fliH
Negative regulator of flii atpase activity; Needed for flagellar regrowth and assembly
 
  
 0.998
fliJ
Flagellar biosynthesis protein flij; The FliJ protein is a flagellar protein that affects chemotactic events. Mutations in FliJ results in failure to respond to chemotactic stimuli
 
  
 0.998
fliQ
Flagellar biosynthesis protein fliq; Required for the assembly of the rivet at the earliest stage of flagellar biosynthesis
 
  
 0.998
fliR
Flagellar biosynthesis protein flir; Role in flagellar biosynthesis
 
  
 0.998
fliF
Flagellar basal-body ms-ring and collar protein; The M ring may be actively involved in energy transduction
 
  
 0.997
fliK
Flagellar hook-length control protein flik; Controls the length of the flagellar hook
 
  
 0.997
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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