STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cblLysr family transcriptional regulator, cys regulon transcriptional activator; May be an accessory regulatory protein within the cys regulon (316 aa)    
Predicted Functional Partners:
nac
Lysr family transcriptional regulator, nitrogen assimilation regulatory protein; Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression (By similarity)
 
   
0.747
yiaU
Putative lysr-type dna-binding transcriptional regulator yiau; Belongs to the LysR transcriptional regulatory family
  
   
 0.680
btuB
Vitamin b12/cobalamin outer membrane transporter; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB. Is also a receptor for bacteriophages BF23 and C1, and for A and E colicins
      
 0.564
cysP
Thiosulfate/sulfate abc transporter periplasmic binding protein cysp; Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. This protein specifically binds thiosulfate and is involved in its transmembrane transport
   
  
 0.561
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite
     
 0.514
ybeF
Putative lysr-type dna-binding transcriptional regulator ybef; Belongs to the LysR transcriptional regulatory family
      
 0.513
cysD
Sulfate adenylyltransferase subunit 2; Belongs to the PAPS reductase family. CysD subfamily
  
  
 0.503
ssuB
Aliphatic sulfonate abc transporter atp binding subunit; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system (Probable)
      
 0.500
ssuC
Aliphatic sulfonate abc transporter membrane subunit; Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane
  
  
 0.492
cysC
Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate
   
  
 0.463
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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