STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yeeSCP4-44 prophage; Putative DNA repair protein, RADC family; Belongs to the UPF0758 family. (148 aa)    
Predicted Functional Partners:
yeeR
CP4-44 prophage; putative membrane protein.
  
  
 0.957
yeeT
CP4-44 prophage; uncharacterized protein; Belongs to the YeeT/YkfH/YpjJ family.
  
  
 0.918
mutS
Methyl-directed mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
   
 0.732
cbeA
CP4-44 prophage; Antitoxin component of a type IV toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of its cognate toxin CbtA (YeeV). It does not bind to the toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles; it is probably retained in the MreB and FtsZ filament bundles. The mechanism has been proposed to require intergenic DNA, in cis, between the cbeA (yeeU) and cbta (yeeV) genes. The intergenic region was not found to be necessary in another study. Also counteracts the morphological defects c [...]
  
  
 0.652
gntX
DNA catabolic protein; Required for the use of extracellular DNA as a nutrient. Has been suggested to be involved in gluconate metabolism ; Belongs to the ComF/GntX family.
 
    0.610
yfbL
Putative aminopeptidase.
      
 0.600
flu
Novel sRNA, CP4-44; Controls colony form variation and autoaggregation. May function as an adhesin.
 
    0.587
mreC
Cell wall structural complex MreBCD transmembrane component MreC; Involved in formation and maintenance of cell shape. Responsible for formation of rod shape. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreC family.
  
  
 0.566
yafZ
UPF0380 protein YafZ; CP4-6 prophage; putative DNA-binding transcriptional regulator;Phage or Prophage Related; Belongs to the UPF0380 family.
   
  
 0.538
ycaI
ComEC family inner membrane protein.
 
  
 0.534
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.