STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yeeEUPF0394 inner membrane protein YeeE; Putative transport system permease protein (352 aa)    
Predicted Functional Partners:
yeeD
annotation not available
  
 0.999
ydjN
Involved in L-cystine transport. Can probably also transport L-cysteine. Mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys).
   
  
 0.913
cysJ
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component
   
  
 0.812
cysP
Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. This protein specifically binds thiosulfate and is involved in its transmembrane transport
   
  
 0.811
cysD
Belongs to the PAPS reductase family. CysD subfamily.
   
  
 0.799
cysN
May be the GTPase, regulating ATP sulfurylase activity
   
    0.789
cysW
Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane
   
    0.760
cysA
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system
   
    0.743
yeeZ
Protein YeeZ; Putative enzyme of sugar metabolism; Protein involved in carbohydrate catabolic process
     
 0.706
plaP
Putrescine importer. Required for induction of type 1 pili- driven surface motility
     
 0.673
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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