STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wbbID-galf:alpha-d-glc beta-1,6-galactofuranosyltransferase; Involved in the transfer of galactofuranose (Galf) onto an alpha-D-gluco-configured acceptor substrate to form a beta-1,6-linkage. It uses n-octyl alpha-D-glucopyranoside as an acceptor substrate for the addition of galactofuranose from the donor substrate UDP- galactofuranose. It is not able to use beta-D-glucopyranoside isomers (330 aa)    
Predicted Functional Partners:
glf
Udp-galactopyranose mutase, fad/nad(p)-binding; Catalyzes the interconversion through a 2-keto intermediate of uridine diphosphogalactopyranose (UDP-GalP) into uridine diphosphogalactofuranose (UDP-GalF)
 
  
 0.997
wzxB
Polyisoprenol-linked o-antigen repeat unit flippase; May be involved in the translocation process of the nascent O-polysaccharide molecules and/or its ligation to lipid A core units
 
  
 0.985
wbbK
Putative lipopolysaccharide biosynthesis protein; May be a glycosyltransferase involved in the transfer of UDP- GalF and UDP-glucose
 
    0.982
wbbH
Putative o-antigen polymerase; May link the O-antigen tetrasaccharide units into long chains, giving rise to typical smooth LPS
  
  
 0.981
wbbJ
Putative lipopolysaccharide biosynthesis o-acetyl transferase; Putative O-acetyltransferase that transfers an O-acetyl group to the O antigen
  
  
 0.976
rfbC
DTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose
  
  
 0.965
rfbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
     
 0.876
rfbB
Dtdp-glucose 4,6 dehydratase, nad(p)-binding; Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6- deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction
  
  
 0.839
rfbD
Dtdp-l-rhamnose synthase, nad(p)-dependent dtdp-4-dehydrorhamnose reductase subunit; Involved in the biosynthesis of the dTDP-L-rhamnose which is an important component of lipopolysaccharide (LPS) (Probable). Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose (By similarity). RmlD uses NADH and NADPH nearly equally well (By similarity)
  
  
 0.790
stfR
Rac prophage; putative membrane protein; Prophage side tail fiber protein homolog StfR; Phage or Prophage Related; Belongs to the tail fiber family
  
   
 0.772
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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