STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wcaLColanic acid/amylovoran biosynthesis glycosyltransferase; Putative colanic acid biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process (406 aa)    
Predicted Functional Partners:
wcaK
Putative colanic acid biosynthesis pyruvyl transferase; Putative galactokinase; Protein involved in colanic acid biosynthetic process
 
   
 0.995
wcaM
Putative colanic acid biosynthesis protein; Protein involved in colanic acid biosynthetic process
 
  
 0.993
wcaC
Putative colanic acid biosynthesis glycosyl transferase WcaC; Protein involved in colanic acid biosynthetic process
 
  
 0.958
wcaA
Putative colanic acid biosynthesis glycosyl transferase WcaA; Putative regulator; Protein involved in colanic acid biosynthetic process
 
 
 0.921
wzxC
M-antigen undecaprenyl disphosphate flippase; Belongs to the polysaccharide synthase family
 
  
 0.919
wcaJ
Putative colanic acid biosysnthesis udp-glucose lipid carrier transferase; Is the initiating enzyme for colanic acid (CA) synthesis. Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55). Also possesses a weak galactose-1-P transferase activity
  
 0.907
wcaI
Putative colanic biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process
 
  
 0.871
wcaE
Putative colanic acid biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process
 
 
 0.843
wcaH
Colanic acid biosynthesis protein wcah; Hydrolyzes both GDP-mannose and GDP-glucose. Could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. Might also be involved in the biosynthesis of the slime polysaccharide colanic acid
 
  
 0.814
wcaD
Putative colanic acid polymerase; Putative enzyme; Phage-related functions and prophages
 
     0.801
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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