STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wcaKPutative colanic acid biosynthesis pyruvyl transferase; Putative galactokinase; Protein involved in colanic acid biosynthetic process (426 aa)    
Predicted Functional Partners:
wcaL
Colanic acid/amylovoran biosynthesis glycosyltransferase; Putative colanic acid biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process
 
   
 0.995
wcaM
Putative colanic acid biosynthesis protein; Protein involved in colanic acid biosynthetic process
 
   
 0.986
wcaC
Putative colanic acid biosynthesis glycosyl transferase WcaC; Protein involved in colanic acid biosynthetic process
 
   
 0.977
wcaJ
Putative colanic acid biosysnthesis udp-glucose lipid carrier transferase; Is the initiating enzyme for colanic acid (CA) synthesis. Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55). Also possesses a weak galactose-1-P transferase activity
 
  
 0.953
wzxC
M-antigen undecaprenyl disphosphate flippase; Belongs to the polysaccharide synthase family
 
  
 0.952
wcaA
Putative colanic acid biosynthesis glycosyl transferase WcaA; Putative regulator; Protein involved in colanic acid biosynthetic process
 
   
 0.941
wcaI
Putative colanic biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process
 
  
 0.868
wcaE
Putative colanic acid biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process
 
  
 0.847
wcaD
Putative colanic acid polymerase; Putative enzyme; Phage-related functions and prophages
 
     0.832
wzc
Colanic acid production tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium. Phosphorylates udg
 
  
 0.816
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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