node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cpsB | cpsG | b2049 | b2048 | Mannose-1-phosphate guanylyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | 0.999 |
cpsB | gmd | b2049 | b2053 | Mannose-1-phosphate guanylyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Gdp-d-mannose dehydratase, nad(p)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose | 0.999 |
cpsB | manA | b2049 | b1613 | Mannose-1-phosphate guanylyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Mannose-6-phosphate isomerase; Involved in the conversion of glucose to GDP-L-fucose, which can be converted to L-fucose, a capsular polysaccharide | 0.938 |
cpsB | wcaG | b2049 | b2052 | Mannose-1-phosphate guanylyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Gdp-l-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction | 0.988 |
cpsB | wcaH | b2049 | b2051 | Mannose-1-phosphate guanylyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Colanic acid biosynthesis protein wcah; Hydrolyzes both GDP-mannose and GDP-glucose. Could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. Might also be involved in the biosynthesis of the slime polysaccharide colanic acid | 0.973 |
cpsB | wcaJ | b2049 | b2047 | Mannose-1-phosphate guanylyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Putative colanic acid biosysnthesis udp-glucose lipid carrier transferase; Is the initiating enzyme for colanic acid (CA) synthesis. Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55). Also possesses a weak galactose-1-P transferase activity | 0.965 |
cpsB | wzxC | b2049 | b2046 | Mannose-1-phosphate guanylyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | M-antigen undecaprenyl disphosphate flippase; Belongs to the polysaccharide synthase family | 0.838 |
cpsG | cpsB | b2048 | b2049 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Mannose-1-phosphate guanylyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | 0.999 |
cpsG | gmd | b2048 | b2053 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Gdp-d-mannose dehydratase, nad(p)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose | 0.983 |
cpsG | manA | b2048 | b1613 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Mannose-6-phosphate isomerase; Involved in the conversion of glucose to GDP-L-fucose, which can be converted to L-fucose, a capsular polysaccharide | 0.992 |
cpsG | manX | b2048 | b1817 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Fused mannose-specific pts enzymes: iia component/iib component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane . The enzyme II ManXYZ PTS system is involved in mannose transport . Also functions as a receptor for bacterial chemotaxis and is required for infection of the cell by bacteriophage lambda where it most likely functions as a pore for penetration of lambda DNA | 0.912 |
cpsG | manY | b2048 | b1818 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Mannose-specific enzyme iic component of pts; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane . The enzyme II ManXYZ PTS system is involved in mannose transport . Also functions as a receptor for bacterial chemotaxis and is required for infection of the cell by bacteriophage lambda where it most likely functions as a pore for penetration of lambda DNA | 0.908 |
cpsG | manZ | b2048 | b1819 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Mannose-specific enzyme iid component of pts; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane . The enzyme II ManXYZ PTS system is involved in mannose transport . Also functions as a receptor for bacterial chemotaxis and is required for infection of the cell by bacteriophage lambda where it most likely functions as a pore for penetration of lambda DNA | 0.909 |
cpsG | wcaG | b2048 | b2052 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Gdp-l-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction | 0.970 |
cpsG | wcaH | b2048 | b2051 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Colanic acid biosynthesis protein wcah; Hydrolyzes both GDP-mannose and GDP-glucose. Could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. Might also be involved in the biosynthesis of the slime polysaccharide colanic acid | 0.941 |
cpsG | wcaJ | b2048 | b2047 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | Putative colanic acid biosysnthesis udp-glucose lipid carrier transferase; Is the initiating enzyme for colanic acid (CA) synthesis. Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55). Also possesses a weak galactose-1-P transferase activity | 0.938 |
cpsG | wzxC | b2048 | b2046 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | M-antigen undecaprenyl disphosphate flippase; Belongs to the polysaccharide synthase family | 0.944 |
gmd | cpsB | b2053 | b2049 | Gdp-d-mannose dehydratase, nad(p)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose | Mannose-1-phosphate guanylyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | 0.999 |
gmd | cpsG | b2053 | b2048 | Gdp-d-mannose dehydratase, nad(p)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid | 0.983 |
gmd | manA | b2053 | b1613 | Gdp-d-mannose dehydratase, nad(p)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose | Mannose-6-phosphate isomerase; Involved in the conversion of glucose to GDP-L-fucose, which can be converted to L-fucose, a capsular polysaccharide | 0.794 |