node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cpsB | cpsG | b2049 | b2048 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid; Belongs to the phosphohexose mutase family. | 0.999 |
cpsB | gmd | b2049 | b2053 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | 0.998 |
cpsB | rfbC | b2049 | b2038 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | dTDP-4-deoxyrhamnose-3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | 0.905 |
cpsB | wcaA | b2049 | b2059 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | 0.920 |
cpsB | wcaG | b2049 | b2052 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily. | 0.973 |
cpsB | wcaH | b2049 | b2051 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | GDP-mannose mannosyl hydrolase; Hydrolyzes both GDP-mannose and GDP-glucose. Could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. Might also be involved in the biosynthesis of the slime polysaccharide colanic acid; Belongs to the Nudix hydrolase family. | 0.941 |
cpsB | wcaI | b2049 | b2050 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Putative colanic biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process. | 0.948 |
cpsB | wcaJ | b2049 | b2047 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Colanic biosynthesis UDP-glucose lipid carrier transferase; Is the initiating enzyme for colanic acid (CA) synthesis. Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55). Also possesses a weak galactose-1-P transferase activity. Belongs to the bacterial sugar transferase family. | 0.992 |
cpsB | wzb | b2049 | b2061 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Colanic acid production protein-tyrosine-phosphatase; Dephosphorylates Wzc. Required for the extracellular polysaccharide colanic acid synthesis, probably involved in the export of colanic acid from the cell to medium. Involved in protection of cells against contact- dependent growth inhibition (CDI), probably due to the loss of a physical impediment to cell-cell contact; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.883 |
cpsB | wzc | b2049 | b2060 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Colanic acid production tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium. Phosphorylates udg. | 0.919 |
cpsG | cpsB | b2048 | b2049 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid; Belongs to the phosphohexose mutase family. | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | 0.999 |
cpsG | gmd | b2048 | b2053 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid; Belongs to the phosphohexose mutase family. | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | 0.962 |
cpsG | rfbC | b2048 | b2038 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid; Belongs to the phosphohexose mutase family. | dTDP-4-deoxyrhamnose-3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | 0.872 |
cpsG | wcaA | b2048 | b2059 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid; Belongs to the phosphohexose mutase family. | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | 0.567 |
cpsG | wcaG | b2048 | b2052 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid; Belongs to the phosphohexose mutase family. | GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily. | 0.946 |
cpsG | wcaH | b2048 | b2051 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid; Belongs to the phosphohexose mutase family. | GDP-mannose mannosyl hydrolase; Hydrolyzes both GDP-mannose and GDP-glucose. Could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. Might also be involved in the biosynthesis of the slime polysaccharide colanic acid; Belongs to the Nudix hydrolase family. | 0.831 |
cpsG | wcaI | b2048 | b2050 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid; Belongs to the phosphohexose mutase family. | Putative colanic biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process. | 0.659 |
cpsG | wcaJ | b2048 | b2047 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid; Belongs to the phosphohexose mutase family. | Colanic biosynthesis UDP-glucose lipid carrier transferase; Is the initiating enzyme for colanic acid (CA) synthesis. Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55). Also possesses a weak galactose-1-P transferase activity. Belongs to the bacterial sugar transferase family. | 0.955 |
cpsG | wzb | b2048 | b2061 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid; Belongs to the phosphohexose mutase family. | Colanic acid production protein-tyrosine-phosphatase; Dephosphorylates Wzc. Required for the extracellular polysaccharide colanic acid synthesis, probably involved in the export of colanic acid from the cell to medium. Involved in protection of cells against contact- dependent growth inhibition (CDI), probably due to the loss of a physical impediment to cell-cell contact; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.718 |
cpsG | wzc | b2048 | b2060 | Phosphomannomutase; Involved in the biosynthesis of the capsular polysaccharide colanic acid; Belongs to the phosphohexose mutase family. | Colanic acid production tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium. Phosphorylates udg. | 0.767 |