node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gmd | wcaA | b2053 | b2059 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | 0.960 |
gmd | wcaB | b2053 | b2058 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Putative transferase; Protein involved in colanic acid biosynthetic process. | 0.863 |
gmd | wcaC | b2053 | b2057 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Putative glycosyl transferase; Protein involved in colanic acid biosynthetic process. | 0.972 |
gmd | wcaE | b2053 | b2055 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Putative colanic acid biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process. | 0.960 |
gmd | wcaF | b2053 | b2054 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Putative transferase; Protein involved in colanic acid biosynthetic process. | 0.972 |
gmd | wcaG | b2053 | b2052 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily. | 0.999 |
gmd | wcaH | b2053 | b2051 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | GDP-mannose mannosyl hydrolase; Hydrolyzes both GDP-mannose and GDP-glucose. Could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. Might also be involved in the biosynthesis of the slime polysaccharide colanic acid; Belongs to the Nudix hydrolase family. | 0.999 |
gmd | wcaI | b2053 | b2050 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Putative colanic biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process. | 0.994 |
gmd | wcaJ | b2053 | b2047 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Colanic biosynthesis UDP-glucose lipid carrier transferase; Is the initiating enzyme for colanic acid (CA) synthesis. Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55). Also possesses a weak galactose-1-P transferase activity. Belongs to the bacterial sugar transferase family. | 0.977 |
gmd | wza | b2053 | b2062 | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Colanic acid export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. | 0.968 |
wcaA | gmd | b2059 | b2053 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | 0.960 |
wcaA | wcaB | b2059 | b2058 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Putative transferase; Protein involved in colanic acid biosynthetic process. | 0.992 |
wcaA | wcaC | b2059 | b2057 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Putative glycosyl transferase; Protein involved in colanic acid biosynthetic process. | 0.996 |
wcaA | wcaE | b2059 | b2055 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Putative colanic acid biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process. | 0.983 |
wcaA | wcaF | b2059 | b2054 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Putative transferase; Protein involved in colanic acid biosynthetic process. | 0.975 |
wcaA | wcaG | b2059 | b2052 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily. | 0.937 |
wcaA | wcaH | b2059 | b2051 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | GDP-mannose mannosyl hydrolase; Hydrolyzes both GDP-mannose and GDP-glucose. Could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. Might also be involved in the biosynthesis of the slime polysaccharide colanic acid; Belongs to the Nudix hydrolase family. | 0.945 |
wcaA | wcaI | b2059 | b2050 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Putative colanic biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process. | 0.986 |
wcaA | wcaJ | b2059 | b2047 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Colanic biosynthesis UDP-glucose lipid carrier transferase; Is the initiating enzyme for colanic acid (CA) synthesis. Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55). Also possesses a weak galactose-1-P transferase activity. Belongs to the bacterial sugar transferase family. | 0.981 |
wcaA | wza | b2059 | b2062 | Putative glycosyl transferase; Putative regulator; Protein involved in colanic acid biosynthetic process. | Colanic acid export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. | 0.980 |