node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cpsB | etk | b2049 | b0981 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Tyrosine-protein kinase, role in O-antigen capsule formation; Protein involved in protein modification process; Belongs to the etk/wzc family. | 0.627 |
cpsB | wcaJ | b2049 | b2047 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Colanic biosynthesis UDP-glucose lipid carrier transferase; Is the initiating enzyme for colanic acid (CA) synthesis. Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55). Also possesses a weak galactose-1-P transferase activity. Belongs to the bacterial sugar transferase family. | 0.992 |
cpsB | wza | b2049 | b2062 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Colanic acid export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. | 0.870 |
cpsB | wzb | b2049 | b2061 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Colanic acid production protein-tyrosine-phosphatase; Dephosphorylates Wzc. Required for the extracellular polysaccharide colanic acid synthesis, probably involved in the export of colanic acid from the cell to medium. Involved in protection of cells against contact- dependent growth inhibition (CDI), probably due to the loss of a physical impediment to cell-cell contact; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.883 |
cpsB | wzc | b2049 | b2060 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Colanic acid production tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium. Phosphorylates udg. | 0.919 |
cpsB | wzxB | b2049 | b2037 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Putative polisoprenol-linked O-antigen transporter; May be involved in the translocation process of the nascent O-polysaccharide molecules and/or its ligation to lipid A core units. | 0.587 |
cpsB | wzxC | b2049 | b2046 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | Putative colanic acid exporter; Probable export protein; Belongs to the polysaccharide synthase family. | 0.800 |
cpsB | wzxE | b2049 | b3792 | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | O-antigen translocase; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA). Required for the assembly of the phosphoglyceride-linked form of ECA (ECA(PG)) and the water-soluble cyclic form of ECA (ECA(CYC)). Could also mediate the translocation of Und-PP-GlcNAc. | 0.438 |
etk | cpsB | b0981 | b2049 | Tyrosine-protein kinase, role in O-antigen capsule formation; Protein involved in protein modification process; Belongs to the etk/wzc family. | Mannose-1-phosphate guanyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid. | 0.627 |
etk | etp | b0981 | b0982 | Tyrosine-protein kinase, role in O-antigen capsule formation; Protein involved in protein modification process; Belongs to the etk/wzc family. | O-antigen capsule forming protein-tyrosine-phosphatase; Dephosphorylates etk; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.995 |
etk | wcaJ | b0981 | b2047 | Tyrosine-protein kinase, role in O-antigen capsule formation; Protein involved in protein modification process; Belongs to the etk/wzc family. | Colanic biosynthesis UDP-glucose lipid carrier transferase; Is the initiating enzyme for colanic acid (CA) synthesis. Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55). Also possesses a weak galactose-1-P transferase activity. Belongs to the bacterial sugar transferase family. | 0.961 |
etk | wza | b0981 | b2062 | Tyrosine-protein kinase, role in O-antigen capsule formation; Protein involved in protein modification process; Belongs to the etk/wzc family. | Colanic acid export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. | 0.919 |
etk | wzb | b0981 | b2061 | Tyrosine-protein kinase, role in O-antigen capsule formation; Protein involved in protein modification process; Belongs to the etk/wzc family. | Colanic acid production protein-tyrosine-phosphatase; Dephosphorylates Wzc. Required for the extracellular polysaccharide colanic acid synthesis, probably involved in the export of colanic acid from the cell to medium. Involved in protection of cells against contact- dependent growth inhibition (CDI), probably due to the loss of a physical impediment to cell-cell contact; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.963 |
etk | wzc | b0981 | b2060 | Tyrosine-protein kinase, role in O-antigen capsule formation; Protein involved in protein modification process; Belongs to the etk/wzc family. | Colanic acid production tyrosine-protein kinase; Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium. Phosphorylates udg. | 0.946 |
etk | wzxB | b0981 | b2037 | Tyrosine-protein kinase, role in O-antigen capsule formation; Protein involved in protein modification process; Belongs to the etk/wzc family. | Putative polisoprenol-linked O-antigen transporter; May be involved in the translocation process of the nascent O-polysaccharide molecules and/or its ligation to lipid A core units. | 0.545 |
etk | wzxC | b0981 | b2046 | Tyrosine-protein kinase, role in O-antigen capsule formation; Protein involved in protein modification process; Belongs to the etk/wzc family. | Putative colanic acid exporter; Probable export protein; Belongs to the polysaccharide synthase family. | 0.519 |
etk | wzxE | b0981 | b3792 | Tyrosine-protein kinase, role in O-antigen capsule formation; Protein involved in protein modification process; Belongs to the etk/wzc family. | O-antigen translocase; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA). Required for the assembly of the phosphoglyceride-linked form of ECA (ECA(PG)) and the water-soluble cyclic form of ECA (ECA(CYC)). Could also mediate the translocation of Und-PP-GlcNAc. | 0.483 |
etp | etk | b0982 | b0981 | O-antigen capsule forming protein-tyrosine-phosphatase; Dephosphorylates etk; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Tyrosine-protein kinase, role in O-antigen capsule formation; Protein involved in protein modification process; Belongs to the etk/wzc family. | 0.995 |
etp | wza | b0982 | b2062 | O-antigen capsule forming protein-tyrosine-phosphatase; Dephosphorylates etk; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Colanic acid export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium. | 0.876 |
etp | wzb | b0982 | b2061 | O-antigen capsule forming protein-tyrosine-phosphatase; Dephosphorylates etk; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Colanic acid production protein-tyrosine-phosphatase; Dephosphorylates Wzc. Required for the extracellular polysaccharide colanic acid synthesis, probably involved in the export of colanic acid from the cell to medium. Involved in protection of cells against contact- dependent growth inhibition (CDI), probably due to the loss of a physical impediment to cell-cell contact; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.907 |