STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yegPUPF0339 family protein; Belongs to the UPF0339 family. Duplicated subfamily. (110 aa)    
Predicted Functional Partners:
ygaU
Uncharacterized protein; Highly specific potassium binding protein that is required for normal growth in the presence of high levels of external K(+). May act as a sensor of cytoplasmic K(+) concentration. Binds a single K(+) ion, which induces a large conformational change. Can also bind the larger alkali metal ions Rb(+) and Cs(+), and NH(4)(+). May be involved in the regulation of peptidoglycan cross-linking.
 
   0.956
ycgB
SpoVR family stationary phase protein; To B.subtilis SpoVR.
   
  
 0.918
msyB
Multicopy suppressor of secY and secA; Could participate in the normal pathway of protein export.
   
    0.844
ycaC
Putative isochorismatase family hydrolase; Protein involved in cellular amino acid catabolic process.
   
  
 0.815
otsA
Trehalose-6-phosphate synthase; Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6- phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor. Essential for viability of the cells at low temperatures and at elevated osmotic strength. Belongs to the glycosyltransferase 20 family.
   
  
 0.791
psiF
PsiF family protein; Induced by phosphate starvation; Protein involved in phosphorus metabolic process and response to starvation.
   
    0.780
ydiZ
Uncharacterized protein.
   
    0.777
yedP
Putative mannosyl-3-phosphoglycerate phosphatase.
   
    0.772
yohC
Yip1 family inner membrane protein.
   
  
 0.770
ybaA
DUF1428 family protein.
   
  
 0.756
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: medium (64%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.