STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yeiEPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (293 aa)    
Predicted Functional Partners:
yeiH
UPF0324 family inner membrane protein.
 
    0.811
hdfR
flhDC operon transcriptional repressor; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon. Belongs to the LysR transcriptional regulatory family.
  
     0.766
xapR
Transcriptional activator of xapAB; Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine.
  
     0.747
yiaN
2,3-diketo-L-gulonate TRAP transporter large permease protein; Part of the tripartite ATP-independent periplasmic (TRAP) transport system YiaMNO involved in the uptake of 2,3-diketo-L- gulonate.
   
  
 0.733
lysP
Lysine transporter; Permease that is involved in the transport across the cytoplasmic membrane of lysine; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
     
 0.727
yiaL
DUF386 family protein; Putative lipase; Belongs to the TabA/YhcH/YiaL family.
  
   
 0.673
yiaO
2,3-diketo-L-gulonate-binding periplasmic protein; Part of the tripartite ATP-independent periplasmic (TRAP) transport system YiaMNO involved in the uptake of 2,3-diketo-L- gulonate. This protein specifically binds 2,3-diketo-L-gulonate. Is not able to bind either L-ascorbate or dehydroascorbate. Belongs to the bacterial solute-binding protein 7 family.
      
 0.645
yddM
Putative DNA-binding transcriptional regulator; Protein involved in regulation of transcription, DNA-dependent; Belongs to the VapA/VapI family.
      
 0.630
ybaQ
Putative DNA-binding transcriptional regulator; Belongs to the VapA/VapI family.
      
 0.622
pgrR
Murein peptide degradation regulator; Regulates the expression of genes involved in peptidoglycan (PG) degradation. Could play a role in switch control between recycling and degradation of PG peptides. Negatively regulates the expression of the ycjY-ymjD-ymjC-mpaA operon by binding to the PgrR-box. In addition, other genes are predicted to be under the control of PgrR, including genes related to membrane formation and function.
  
     0.610
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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