STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yeiIPutative kinase; Belongs to the carbohydrate kinase PfkB family. (362 aa)    
Predicted Functional Partners:
nfo
Endonuclease IV with intrinsic 3'-5' exonuclease activity; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
  
    0.927
yjjW
Putative activating enzyme; Protein involved in anaerobic respiration and protein modification process; Belongs to the organic radical-activating enzymes family.
  
  
 0.840
psuG
Pseudouridine 5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
 
     0.810
yfhL
Putative 4Fe-4S cluster-containing protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
     
 0.733
uidC
Putative outer membrane porin for beta-glucuronides porin protein; Enhances the activity of the UidB (GusB) glucuronide transporter, on its own however it has no transport activity. Glucuronide transport does not occur in strain K12 due to a variant at position 100 of the UidB (GusB, AC P0CE44, AC P0CE45) protein.
      
 0.644
yhaL
Uncharacterized protein.
      
 0.641
rbsD
D-ribose pyranase; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. It also catalyzes the conversion between beta- allofuranose and beta-allopyranose; Belongs to the RbsD / FucU family. RbsD subfamily.
 
  
 0.619
yjjI
DUF3029 family protein, putative glycine radical enzyme.
  
     0.614
ybhK
Putative CofD superfamily transferase; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
      
 0.594
yeiH
UPF0324 family inner membrane protein.
  
    0.566
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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