STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psuTPutative nucleoside transporter; Could be involved in pseudouridine transport; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (416 aa)    
Predicted Functional Partners:
psuK
Pseudouridine kinase; Catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP).
  
  
 0.834
psuG
Pseudouridine 5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
  
  
 0.830
yjjI
DUF3029 family protein, putative glycine radical enzyme.
      
 0.732
frlA
Putative fructoselysine transporter; Is likely involved in the transport of fructoselysine and psicoselysine to the cytoplasm, where they are degraded.
      
 0.645
yjjJ
Putative protein kinase; Toxic when overexpressed in E.coli, leading to long filamentous cells. The toxic effect is neutralized by non-cognate antitoxin HipB. Does not seem to inhibit DNA, RNA or protein synthesis, and unlike paralogous toxin HipA its toxic activity is not counteracted by overexpression of GltX. Binds DNA. Might be a protein kinase (By similarity).
      
 0.644
yqeG
Putative transporter protein.
      
 0.591
yhaO
Putative transporter; Plays a role in L-cysteine detoxification. May transport both D- and L-serine (By similarity). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
   
  
 0.531
yifK
Putative APC family amino acid transporter; Probable amino-acid or metabolite transport protein; Belongs to the amino acid-polyamine-organocation (APC) superfamily.
      
 0.530
yagU
DUF1440 family inner membrane acid resistance protein.
      
 0.526
frlB
fructoselysine-6-P-deglycase; Catalyzes the reversible conversion of fructoselysine 6- phosphate to glucose 6-phosphate and lysine. Functions in a fructoselysine degradation pathway that allows E.coli to grow on fructoselysine or psicoselysine.
      
 0.524
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.