STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
setBMfs transporter, set family, sugar efflux transporter; Involved in the efflux of sugars. The physiological role may be the detoxification of non-metabolizable sugar analogs. Can transport lactose and glucose (393 aa)    
Predicted Functional Partners:
ycaD
Uncharacterized MFS-type transporter YcaD; Putative transport; Not classified
  
 
 
 0.674
mreB
Cell wall structural complex mrebcd, actin-like component mreb; Forms membrane-associated dynamic filaments that are essential for cell shape determination Acts by regulating cell wall synthesis and cell elongation, and thus cell shape . A feedback loop between cell geometry and MreB localization maintains elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature . Filaments rotate around the cell circumference in concert with the cell wall synthesis enzymes. The process is driven by the cell wall synthesis machinery and does not depend on MreB polym [...]
      
 0.669
fruB
Fused fructose-specific pts enzymes: iia component/hpr component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport
 
   
 0.628
ydeA
Mfs transporter, dha1 family, l-arabinose/isopropyl-beta-d-thiogalactopyranoside export protein; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites. Transports L-arabinose and to a lesser extent IPTG. Seems to contribute to the control of the arabinose regulon
  
   
 0.625
yhhS
Putative arabinose efflux transporter; Confers high-level resistance to glyphosate when overexpressed . Overexpression has no effect on intracellular arabinose concentrations
  
 
 
 0.610
yfcJ
Putative arabinose efflux transporter; Overexpression has no effect on intracellular arabinose concentrations
      
 0.607
yfgJ
Zinc ribbon domain-containing protein yfgj; Uncharacterized protein YfgJ; Protein involved in biotin carboxyl carrier protein biosynthetic process
  
     0.578
agaV
N-acetyl-d-galactosamine specific pts enzyme iib component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylgalactosamine transport
      
 0.578
yajR
Inner membrane transport protein YajR; Putative transport protein; Protein involved in response to drug
      
 0.563
ygcS
Putative mfs sugar transporter; Inner membrane metabolite transport protein YgcS; Putative transport protein
    
 
 0.546
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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