STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
napGFerredoxin-type protein; Required for electron transfer from ubiquinol, via NapC, to the periplasmic nitrate reductase NapAB complex. (231 aa)    
Predicted Functional Partners:
napB
Nitrate reductase, small, cytochrome C550 subunit, periplasmic; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type NapC protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Essential for periplasmic nitrate reduction with nitrate as the terminal electron acceptor; Belongs to the NapB family.
 
 
 0.999
napH
Ferredoxin-type protein; Required for electron transfer from ubiquinol, via NapC, to the periplasmic nitrate reductase NapAB complex.
 
 0.999
napC
Quinol dehydrogenase, electron source for NapAB; Mediates electron flow from quinones to the NapAB complex.
 
  
 0.998
napA
Nitrate reductase, periplasmic, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
 
 0.998
napD
Assembly protein for periplasmic nitrate reductase; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export. May have a role in the insertion of the NapA molybdenum cofactor.
  
  
 0.993
napF
Ferredoxin-type protein, role in electron transfer to periplasmic nitrate reductase NapA; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm. Is not involved in the electron transfer from menaquinol or ubiquinol to the periplasmic nitrate reductase.
 
  
0.938
ccmA
Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.
  
  
 0.851
ccmB
Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
  
    0.822
nrfC
Formate-dependent nitrite reductase, 4Fe4S subunit; Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes.
  
  
 0.780
torA
Trimethylamine N-oxide (TMAO) reductase I, catalytic subunit; Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.
  
 
 0.767
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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