STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfaPannotation not available (258 aa)    
Predicted Functional Partners:
yfaQ
annotation not available
 
  
 0.998
yfaA
annotation not available
 
  
 0.988
yfaT
DUF1175 domain-containing protein YfaT; To P.aeruginosa PA4490 and T.maritima TM0986
 
  
 0.980
pbpC
Penicillin-insensitive murein repair transglycosylase; Cell wall formation. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a transpeptidase C-terminal domain which may not be functional
      
 0.826
lsrB
Autoinducer-2 ABC transporter periplasmic binding protein; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (Probable)
      
 0.732
yfhM
Bacterial alpha2-macroglobulin colonization factor ecam; Protects the bacterial cell from host peptidases . Acts by a 'trapping' mechanism. Cleavage of the bait-region domain by host peptidases leads to a global conformational change, which results in entrapment of the host peptidase and activation of the thioester bond that covalently binds the attacking host peptidase Trapped peptidases are still active except against very large substrates . May protect the entire periplam, including the lipoproteins anchored to the periplasmic side of the outer membrane, against intruding endopeptidases
  
  
 0.676
ydhQ
Autotransporter adhesin-related protein; Uncharacterized protein YdhQ; Possible enzyme
  
     0.616
yfbM
annotation not available
  
     0.559
yidX
Putative lipoprotein yidx; Uncharacterized protein YidX; Putative replicase EC 2.7.-
  
     0.468
hofN
Dna catabolic putative fimbrial assembly protein; Required for the use of extracellular DNA as a nutrient
  
     0.462
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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