node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
yfaA | yfaP | b2230 | b2225 | DUF2138 family protein, putative host defense protein. | DUF2135 family protein, putative host defense protein. | 0.956 |
yfaA | yfaQ | b2230 | b2226 | DUF2138 family protein, putative host defense protein. | Tandem DUF2300 domain protein, putative host defense protein. | 0.935 |
yfaA | yfaT | b2230 | b2229 | DUF2138 family protein, putative host defense protein. | Uncharacterized protein YfaT; Pseudogene, bacterial alpha2-macroglobulin YfaS variant family; putative membrane protein; To P.aeruginosa PA4490 and T.maritima TM0986. | 0.986 |
yfaA | yfhM | b2230 | b2520 | DUF2138 family protein, putative host defense protein. | Bacterial alpha2-macroglobulin colonization factor ECAM; Protects the bacterial cell from host peptidases. Acts by a 'trapping' mechanism. Cleavage of the bait-region domain by host peptidases leads to a global conformational change, which results in entrapment of the host peptidase and activation of the thioester bond that covalently binds the attacking host peptidase. Trapped peptidases are still active except against very large substrates. May protect the entire periplam, including the lipoproteins anchored to the periplasmic side of the outer membrane, against intruding endopeptidases. | 0.695 |
yfaP | yfaA | b2225 | b2230 | DUF2135 family protein, putative host defense protein. | DUF2138 family protein, putative host defense protein. | 0.956 |
yfaP | yfaQ | b2225 | b2226 | DUF2135 family protein, putative host defense protein. | Tandem DUF2300 domain protein, putative host defense protein. | 0.987 |
yfaP | yfaT | b2225 | b2229 | DUF2135 family protein, putative host defense protein. | Uncharacterized protein YfaT; Pseudogene, bacterial alpha2-macroglobulin YfaS variant family; putative membrane protein; To P.aeruginosa PA4490 and T.maritima TM0986. | 0.882 |
yfaP | yfhM | b2225 | b2520 | DUF2135 family protein, putative host defense protein. | Bacterial alpha2-macroglobulin colonization factor ECAM; Protects the bacterial cell from host peptidases. Acts by a 'trapping' mechanism. Cleavage of the bait-region domain by host peptidases leads to a global conformational change, which results in entrapment of the host peptidase and activation of the thioester bond that covalently binds the attacking host peptidase. Trapped peptidases are still active except against very large substrates. May protect the entire periplam, including the lipoproteins anchored to the periplasmic side of the outer membrane, against intruding endopeptidases. | 0.679 |
yfaQ | yfaA | b2226 | b2230 | Tandem DUF2300 domain protein, putative host defense protein. | DUF2138 family protein, putative host defense protein. | 0.935 |
yfaQ | yfaP | b2226 | b2225 | Tandem DUF2300 domain protein, putative host defense protein. | DUF2135 family protein, putative host defense protein. | 0.987 |
yfaQ | yfaT | b2226 | b2229 | Tandem DUF2300 domain protein, putative host defense protein. | Uncharacterized protein YfaT; Pseudogene, bacterial alpha2-macroglobulin YfaS variant family; putative membrane protein; To P.aeruginosa PA4490 and T.maritima TM0986. | 0.922 |
yfaQ | yfhM | b2226 | b2520 | Tandem DUF2300 domain protein, putative host defense protein. | Bacterial alpha2-macroglobulin colonization factor ECAM; Protects the bacterial cell from host peptidases. Acts by a 'trapping' mechanism. Cleavage of the bait-region domain by host peptidases leads to a global conformational change, which results in entrapment of the host peptidase and activation of the thioester bond that covalently binds the attacking host peptidase. Trapped peptidases are still active except against very large substrates. May protect the entire periplam, including the lipoproteins anchored to the periplasmic side of the outer membrane, against intruding endopeptidases. | 0.589 |
yfaT | yfaA | b2229 | b2230 | Uncharacterized protein YfaT; Pseudogene, bacterial alpha2-macroglobulin YfaS variant family; putative membrane protein; To P.aeruginosa PA4490 and T.maritima TM0986. | DUF2138 family protein, putative host defense protein. | 0.986 |
yfaT | yfaP | b2229 | b2225 | Uncharacterized protein YfaT; Pseudogene, bacterial alpha2-macroglobulin YfaS variant family; putative membrane protein; To P.aeruginosa PA4490 and T.maritima TM0986. | DUF2135 family protein, putative host defense protein. | 0.882 |
yfaT | yfaQ | b2229 | b2226 | Uncharacterized protein YfaT; Pseudogene, bacterial alpha2-macroglobulin YfaS variant family; putative membrane protein; To P.aeruginosa PA4490 and T.maritima TM0986. | Tandem DUF2300 domain protein, putative host defense protein. | 0.922 |
yfaT | yfhM | b2229 | b2520 | Uncharacterized protein YfaT; Pseudogene, bacterial alpha2-macroglobulin YfaS variant family; putative membrane protein; To P.aeruginosa PA4490 and T.maritima TM0986. | Bacterial alpha2-macroglobulin colonization factor ECAM; Protects the bacterial cell from host peptidases. Acts by a 'trapping' mechanism. Cleavage of the bait-region domain by host peptidases leads to a global conformational change, which results in entrapment of the host peptidase and activation of the thioester bond that covalently binds the attacking host peptidase. Trapped peptidases are still active except against very large substrates. May protect the entire periplam, including the lipoproteins anchored to the periplasmic side of the outer membrane, against intruding endopeptidases. | 0.717 |
yfhM | yfaA | b2520 | b2230 | Bacterial alpha2-macroglobulin colonization factor ECAM; Protects the bacterial cell from host peptidases. Acts by a 'trapping' mechanism. Cleavage of the bait-region domain by host peptidases leads to a global conformational change, which results in entrapment of the host peptidase and activation of the thioester bond that covalently binds the attacking host peptidase. Trapped peptidases are still active except against very large substrates. May protect the entire periplam, including the lipoproteins anchored to the periplasmic side of the outer membrane, against intruding endopeptidases. | DUF2138 family protein, putative host defense protein. | 0.695 |
yfhM | yfaP | b2520 | b2225 | Bacterial alpha2-macroglobulin colonization factor ECAM; Protects the bacterial cell from host peptidases. Acts by a 'trapping' mechanism. Cleavage of the bait-region domain by host peptidases leads to a global conformational change, which results in entrapment of the host peptidase and activation of the thioester bond that covalently binds the attacking host peptidase. Trapped peptidases are still active except against very large substrates. May protect the entire periplam, including the lipoproteins anchored to the periplasmic side of the outer membrane, against intruding endopeptidases. | DUF2135 family protein, putative host defense protein. | 0.679 |
yfhM | yfaQ | b2520 | b2226 | Bacterial alpha2-macroglobulin colonization factor ECAM; Protects the bacterial cell from host peptidases. Acts by a 'trapping' mechanism. Cleavage of the bait-region domain by host peptidases leads to a global conformational change, which results in entrapment of the host peptidase and activation of the thioester bond that covalently binds the attacking host peptidase. Trapped peptidases are still active except against very large substrates. May protect the entire periplam, including the lipoproteins anchored to the periplasmic side of the outer membrane, against intruding endopeptidases. | Tandem DUF2300 domain protein, putative host defense protein. | 0.589 |
yfhM | yfaT | b2520 | b2229 | Bacterial alpha2-macroglobulin colonization factor ECAM; Protects the bacterial cell from host peptidases. Acts by a 'trapping' mechanism. Cleavage of the bait-region domain by host peptidases leads to a global conformational change, which results in entrapment of the host peptidase and activation of the thioester bond that covalently binds the attacking host peptidase. Trapped peptidases are still active except against very large substrates. May protect the entire periplam, including the lipoproteins anchored to the periplasmic side of the outer membrane, against intruding endopeptidases. | Uncharacterized protein YfaT; Pseudogene, bacterial alpha2-macroglobulin YfaS variant family; putative membrane protein; To P.aeruginosa PA4490 and T.maritima TM0986. | 0.717 |