STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfaZannotation not available (180 aa)    
Predicted Functional Partners:
nudI
Nucleoside triphosphatase NudI; Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP); Belongs to the Nudix hydrolase family. NudI subfamily
     
 0.808
rclB
Uncharacterized protein RclB; Probably involved in reactive chlorine species (RCS) stress resistance; Belongs to the BhsA/McbA family
      
 0.803
ykfG
UPF0758 protein YkfG; Putative DNA repair protein; Belongs to the UPF0758 family
      
 0.801
ypjD
annotation not available
  
   
 0.785
ybfE
Uncharacterized protein YbfE; Protein involved in SOS response
      
 0.754
ttdB
L-tartrate dehydratase, subunit B; Protein involved in fermentation
      
 0.753
yffL
Uncharacterized protein YffL; Phage or Prophage Related
      
 0.751
rclA
Probable pyridine nucleotide-disulfide oxidoreductase RclA; Probably involved in reactive chlorine species (RCS) stress resistance
      
 0.750
intZ
Prophage integrase IntZ; Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome
      
 0.749
ygdH
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of diverse pyrimidine and purine nucleotide 5'-monophosphates, to form ribose 5-phosphate and the corresponding free base. Can use AMP, GMP, IMP, CMP, dTMP and UMP as substrates. Cannot catalyze the reverse reactions. Is required for optimal growth in glucose minimal medium, possibly because it contributes to nucleoside pool homeostasis by degrading excess nucleotides and feeding back the ribose moiety to catabolism
      
 0.749
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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