node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
rplD | rplW | b3319 | b3318 | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family. | 50S ribosomal subunit protein L23; One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor for Ffh binding to the ribosome (SRP54, and and to nascent polypeptide chains. Belongs to the universal ribosomal protein uL23 family. | 0.999 |
rplD | rplY | b3319 | b2185 | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family. | 50S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Binds to the 5S rRNA independently of L5 and L18. Not required for binding of the 5S rRNA/L5/L18 subcomplex to 23S rRNA. | 0.996 |
rplD | rpmB | b3319 | b3637 | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family. | 50S ribosomal subunit protein L28; Protein involved in structural constituent of ribosome and translation. | 0.998 |
rplD | rpsB | b3319 | b0169 | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family. | 30S ribosomal subunit protein S2; Required for ribosomal protein S1 to bind to the 30S subunit. | 0.999 |
rplD | rpsG | b3319 | b3341 | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family. | 30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, where it has been shown to contact mRNA. Has been shown to contact tRNA in both the P and E sites; it probably blocks exit of the E site tRNA. | 0.999 |
rplD | rpsJ | b3319 | b3321 | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family. | 30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. In addition, in complex with NusB, is involved in the regulation of ribosomal RNA (rRNA) biosynthesis by transcriptional antitermination. S10 binds RNA non-specifically and increases the affinity of NusB for the boxA RNA sequence. S10 may constitute the critical antitermination component of the NusB-S10 complex. Belongs to the universal ribosomal protein uS10 family. | 0.999 |
rplD | rpsN | b3319 | b3307 | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family. | 30S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. | 0.999 |
rplD | rpsU | b3319 | b3065 | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family. | 30S ribosomal subunit protein S21; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bS21 family. | 0.986 |
rplD | smrB | b3319 | b2331 | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family. | Putative DNA endonuclease; Belongs to the UPF0115 family. | 0.841 |
rplW | rplD | b3318 | b3319 | 50S ribosomal subunit protein L23; One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor for Ffh binding to the ribosome (SRP54, and and to nascent polypeptide chains. Belongs to the universal ribosomal protein uL23 family. | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family. | 0.999 |
rplW | rplY | b3318 | b2185 | 50S ribosomal subunit protein L23; One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor for Ffh binding to the ribosome (SRP54, and and to nascent polypeptide chains. Belongs to the universal ribosomal protein uL23 family. | 50S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Binds to the 5S rRNA independently of L5 and L18. Not required for binding of the 5S rRNA/L5/L18 subcomplex to 23S rRNA. | 0.995 |
rplW | rpmB | b3318 | b3637 | 50S ribosomal subunit protein L23; One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor for Ffh binding to the ribosome (SRP54, and and to nascent polypeptide chains. Belongs to the universal ribosomal protein uL23 family. | 50S ribosomal subunit protein L28; Protein involved in structural constituent of ribosome and translation. | 0.996 |
rplW | rpsB | b3318 | b0169 | 50S ribosomal subunit protein L23; One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor for Ffh binding to the ribosome (SRP54, and and to nascent polypeptide chains. Belongs to the universal ribosomal protein uL23 family. | 30S ribosomal subunit protein S2; Required for ribosomal protein S1 to bind to the 30S subunit. | 0.999 |
rplW | rpsG | b3318 | b3341 | 50S ribosomal subunit protein L23; One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor for Ffh binding to the ribosome (SRP54, and and to nascent polypeptide chains. Belongs to the universal ribosomal protein uL23 family. | 30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, where it has been shown to contact mRNA. Has been shown to contact tRNA in both the P and E sites; it probably blocks exit of the E site tRNA. | 0.999 |
rplW | rpsJ | b3318 | b3321 | 50S ribosomal subunit protein L23; One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor for Ffh binding to the ribosome (SRP54, and and to nascent polypeptide chains. Belongs to the universal ribosomal protein uL23 family. | 30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. In addition, in complex with NusB, is involved in the regulation of ribosomal RNA (rRNA) biosynthesis by transcriptional antitermination. S10 binds RNA non-specifically and increases the affinity of NusB for the boxA RNA sequence. S10 may constitute the critical antitermination component of the NusB-S10 complex. Belongs to the universal ribosomal protein uS10 family. | 0.999 |
rplW | rpsN | b3318 | b3307 | 50S ribosomal subunit protein L23; One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor for Ffh binding to the ribosome (SRP54, and and to nascent polypeptide chains. Belongs to the universal ribosomal protein uL23 family. | 30S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. | 0.999 |
rplW | rpsU | b3318 | b3065 | 50S ribosomal subunit protein L23; One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor for Ffh binding to the ribosome (SRP54, and and to nascent polypeptide chains. Belongs to the universal ribosomal protein uL23 family. | 30S ribosomal subunit protein S21; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bS21 family. | 0.981 |
rplW | smrB | b3318 | b2331 | 50S ribosomal subunit protein L23; One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor for Ffh binding to the ribosome (SRP54, and and to nascent polypeptide chains. Belongs to the universal ribosomal protein uL23 family. | Putative DNA endonuclease; Belongs to the UPF0115 family. | 0.804 |
rplY | rplD | b2185 | b3319 | 50S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Binds to the 5S rRNA independently of L5 and L18. Not required for binding of the 5S rRNA/L5/L18 subcomplex to 23S rRNA. | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family. | 0.996 |
rplY | rplW | b2185 | b3318 | 50S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Binds to the 5S rRNA independently of L5 and L18. Not required for binding of the 5S rRNA/L5/L18 subcomplex to 23S rRNA. | 50S ribosomal subunit protein L23; One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor for Ffh binding to the ribosome (SRP54, and and to nascent polypeptide chains. Belongs to the universal ribosomal protein uL23 family. | 0.995 |