node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fadI | fadJ | b2342 | b2341 | beta-ketoacyl-CoA thiolase, anaerobic, subunit; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. Strongly involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate and weakly involved in the aerobic degradation of long-chain fatty acids. Belongs to the thiolase-like superfamily. Thiolase family. | enoyl-CoA hydratase/epimerase and isomerase/3-hydroxyacyl-CoA dehydrogenase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Strongly involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate and weakly involved in the aerobic degradation of long-chain fatty acids; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.999 |
fadI | yfcZ | b2342 | b2343 | beta-ketoacyl-CoA thiolase, anaerobic, subunit; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. Strongly involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate and weakly involved in the aerobic degradation of long-chain fatty acids. Belongs to the thiolase-like superfamily. Thiolase family. | UPF0381 family protein; Belongs to the UPF0381 family. | 0.494 |
fadJ | fadI | b2341 | b2342 | enoyl-CoA hydratase/epimerase and isomerase/3-hydroxyacyl-CoA dehydrogenase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Strongly involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate and weakly involved in the aerobic degradation of long-chain fatty acids; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | beta-ketoacyl-CoA thiolase, anaerobic, subunit; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. Strongly involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate and weakly involved in the aerobic degradation of long-chain fatty acids. Belongs to the thiolase-like superfamily. Thiolase family. | 0.999 |
fadJ | yfcZ | b2341 | b2343 | enoyl-CoA hydratase/epimerase and isomerase/3-hydroxyacyl-CoA dehydrogenase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Strongly involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate and weakly involved in the aerobic degradation of long-chain fatty acids; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | UPF0381 family protein; Belongs to the UPF0381 family. | 0.493 |
potG | yfcZ | b0855 | b2343 | Putrescine ABC transporter ATPase; Part of the binding-protein-dependent transport system for putrescine. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. | UPF0381 family protein; Belongs to the UPF0381 family. | 0.457 |
rppH | rpsT | b2830 | b0023 | RNA pyrophosphohydrolase; Master regulator of 5'-end-dependent mRNA decay. Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage. Preferentially hydrolyzes diadenosine penta-phosphate with ATP as one of the reaction products. Also able to hydrolyze diadenosine hexa- and tetra-phosphate. Has no activity on diadenosine tri-phosphate, ADP-ribose, NADH and UDP-glucose. In an RNase PH (rph) wild-type strain background, RppH is not req [...] | 30S ribosomal subunit protein S20; Binds directly to 16S ribosomal RNA. | 0.693 |
rppH | yeiP | b2830 | b2171 | RNA pyrophosphohydrolase; Master regulator of 5'-end-dependent mRNA decay. Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage. Preferentially hydrolyzes diadenosine penta-phosphate with ATP as one of the reaction products. Also able to hydrolyze diadenosine hexa- and tetra-phosphate. Has no activity on diadenosine tri-phosphate, ADP-ribose, NADH and UDP-glucose. In an RNase PH (rph) wild-type strain background, RppH is not req [...] | Putative elongation factor; Protein involved in translation. | 0.645 |
rppH | yfcZ | b2830 | b2343 | RNA pyrophosphohydrolase; Master regulator of 5'-end-dependent mRNA decay. Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage. Preferentially hydrolyzes diadenosine penta-phosphate with ATP as one of the reaction products. Also able to hydrolyze diadenosine hexa- and tetra-phosphate. Has no activity on diadenosine tri-phosphate, ADP-ribose, NADH and UDP-glucose. In an RNase PH (rph) wild-type strain background, RppH is not req [...] | UPF0381 family protein; Belongs to the UPF0381 family. | 0.600 |
rpsT | rppH | b0023 | b2830 | 30S ribosomal subunit protein S20; Binds directly to 16S ribosomal RNA. | RNA pyrophosphohydrolase; Master regulator of 5'-end-dependent mRNA decay. Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage. Preferentially hydrolyzes diadenosine penta-phosphate with ATP as one of the reaction products. Also able to hydrolyze diadenosine hexa- and tetra-phosphate. Has no activity on diadenosine tri-phosphate, ADP-ribose, NADH and UDP-glucose. In an RNase PH (rph) wild-type strain background, RppH is not req [...] | 0.693 |
rpsT | yeiP | b0023 | b2171 | 30S ribosomal subunit protein S20; Binds directly to 16S ribosomal RNA. | Putative elongation factor; Protein involved in translation. | 0.788 |
rpsT | yfcZ | b0023 | b2343 | 30S ribosomal subunit protein S20; Binds directly to 16S ribosomal RNA. | UPF0381 family protein; Belongs to the UPF0381 family. | 0.501 |
ydfG | yeiP | b1539 | b2171 | NADP-dependent 3-hydroxy acid dehydrogenase; NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP-dependent oxidation of L- allo-threonine to L-2-amino-3-keto-butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on D-threonine, L-serine, D-serine, D-3-hydroxyisobutyrate, L-3-hydroxyisobutyrate, D-glycerate and L-glycerate. Able to catalyze the reduction of the malonic semialdehyde to 3-hydroxypropionic acid. YdfG is apparently supplementing RutE, the presumed malonic semialdehyde reductase involved in pyrimi [...] | Putative elongation factor; Protein involved in translation. | 0.419 |
ydfG | yfcZ | b1539 | b2343 | NADP-dependent 3-hydroxy acid dehydrogenase; NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP-dependent oxidation of L- allo-threonine to L-2-amino-3-keto-butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on D-threonine, L-serine, D-serine, D-3-hydroxyisobutyrate, L-3-hydroxyisobutyrate, D-glycerate and L-glycerate. Able to catalyze the reduction of the malonic semialdehyde to 3-hydroxypropionic acid. YdfG is apparently supplementing RutE, the presumed malonic semialdehyde reductase involved in pyrimi [...] | UPF0381 family protein; Belongs to the UPF0381 family. | 0.818 |
ydfG | yobF | b1539 | b1824 | NADP-dependent 3-hydroxy acid dehydrogenase; NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP-dependent oxidation of L- allo-threonine to L-2-amino-3-keto-butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on D-threonine, L-serine, D-serine, D-3-hydroxyisobutyrate, L-3-hydroxyisobutyrate, D-glycerate and L-glycerate. Able to catalyze the reduction of the malonic semialdehyde to 3-hydroxypropionic acid. YdfG is apparently supplementing RutE, the presumed malonic semialdehyde reductase involved in pyrimi [...] | DUF2527 family heat-induced protein. | 0.708 |
yeaE | yfcZ | b1781 | b2343 | Aldo-keto reductase, methylglyoxal to acetol, NADPH-dependent; Putative an aldehyde reductase. | UPF0381 family protein; Belongs to the UPF0381 family. | 0.477 |
yeaE | yjcS | b1781 | b4083 | Aldo-keto reductase, methylglyoxal to acetol, NADPH-dependent; Putative an aldehyde reductase. | Metallo-beta-lactamase superfamily protein; Protein involved in sulfur metabolic process; Belongs to the metallo-beta-lactamase superfamily. | 0.456 |
yeiP | rppH | b2171 | b2830 | Putative elongation factor; Protein involved in translation. | RNA pyrophosphohydrolase; Master regulator of 5'-end-dependent mRNA decay. Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage. Preferentially hydrolyzes diadenosine penta-phosphate with ATP as one of the reaction products. Also able to hydrolyze diadenosine hexa- and tetra-phosphate. Has no activity on diadenosine tri-phosphate, ADP-ribose, NADH and UDP-glucose. In an RNase PH (rph) wild-type strain background, RppH is not req [...] | 0.645 |
yeiP | rpsT | b2171 | b0023 | Putative elongation factor; Protein involved in translation. | 30S ribosomal subunit protein S20; Binds directly to 16S ribosomal RNA. | 0.788 |
yeiP | ydfG | b2171 | b1539 | Putative elongation factor; Protein involved in translation. | NADP-dependent 3-hydroxy acid dehydrogenase; NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP-dependent oxidation of L- allo-threonine to L-2-amino-3-keto-butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on D-threonine, L-serine, D-serine, D-3-hydroxyisobutyrate, L-3-hydroxyisobutyrate, D-glycerate and L-glycerate. Able to catalyze the reduction of the malonic semialdehyde to 3-hydroxypropionic acid. YdfG is apparently supplementing RutE, the presumed malonic semialdehyde reductase involved in pyrimi [...] | 0.419 |
yeiP | yfcZ | b2171 | b2343 | Putative elongation factor; Protein involved in translation. | UPF0381 family protein; Belongs to the UPF0381 family. | 0.541 |