STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfdSUncharacterized protein YfdS; Phage or Prophage Related; To the N-terminal region of phage HK97/HK620 Gp37/hpaH (120 aa)    
Predicted Functional Partners:
yfdT
CPS-53 (KpLE1) prophage; protein YfdT; Uncharacterized protein YfdT; Phage or Prophage Related
  
  
 0.985
yfdR
CPS-53 (KpLE1) prophage; 5'-deoxynucleotidase; Uncharacterized protein YfdR; Phage or Prophage Related
     
 0.983
yfdQ
CPS-53 (KpLE1) prophage; protein YfdQ; Uncharacterized protein YfdQ; Phage or Prophage Related
  
  
 0.944
yfdP
CPS-53 (KpLE1) prophage; protein YfdP; To phage T4 y06Q
     
 0.924
ydfR
Qin prophage; protein ydfr; Uncharacterized protein YdfR; Phage or Prophage Related
      
 0.878
yfdK
CPS-53 (KpLE1) prophage; putative tail fiber assembly protein YfdK; To E.coli YmfS
      
 0.829
ymfL
E14 prophage; uncharacterized protein YmfL; Uncharacterized protein YmfL; Phage or Prophage Related
      
 0.739
yfbR
5'-deoxynucleotidase; Essential component of the deoxycytidine triphosphate (dCTP) pathway for de novo synthesis of thymidylate. Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates (dAMP, dGMP, dTMP, dUMP, dIMP and dCMP) and does not dephosphorylate 5'-ribonucleotides or ribonucleoside 3'-monophosphates
      
 0.697
torI
CPS-53 (KpLE1) prophage; prophage CPS-53 recombination directionality factor and response regulator inhibitor; Transcription inhibitory protein for the torCAD operon. Also acts as an excisionase and plays an essential role in the defective prophage CPS53 excision
     
 0.644
dhaK
Dihydroxyacetone kinase, pts-dependent, dihydroxyacetone-binding subunit; Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)- dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP . Binds covalently dihydroxyacetone in hemiaminal linkage . DhaK acts also as corepressor of the transcription activator DhaR by binding to the sensor domain of DhaR . In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity . In the absence of dihydroxyacetone, DhaL- ADP [...]
      
 0.520
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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