STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfdTCPS-53 (KpLE1) prophage; uncharacterized protein. (101 aa)    
Predicted Functional Partners:
yfdS
CPS-53 (KpLE1) prophage; uncharacterized protein; To the N-terminal region of phage HK97/HK620 Gp37/hpaH.
  
  
 0.981
yfdR
CPS-53 (KpLE1) prophage; conserved protein.
  
  
 0.978
yfdP
Uncharacterized protein YfdP; Pseudogene, CPS-53 (KpLE1) prophage; bacteriophage replication protein O family;Phage or Prophage Related; To phage T4 y06Q.
  
  
 0.934
yfdQ
CPS-53 (KpLE1) prophage; uncharacterized protein.
  
  
 0.905
ygeI
Uncharacterized protein.
   
  
 0.897
yfdK
Uncharacterized protein YfdK; Pseudogene, CPS-53 (KpLE1) prophage; tail fiber assembly protein fragment;Phage or Prophage Related; To E.coli YmfS.
   
  
 0.788
ydfR
Qin prophage; uncharacterized protein.
   
  
 0.740
yfdN
Uncharacterized protein YfdN; CPS-53 (KpLE1) prophage; putative methyltransferase;Phage or Prophage Related.
   
  
 0.738
ydcX
DUF2566 family protein; Acts as an orphan toxin which is important for maintaining cell fitness during stress related to the stringent response (decreased amino acid, purine and thymidine availability). Overexpression inhibits cell growth and increases the formation of persister cells. Causes 99.9% of cells to undergo bacterial lysis within 2 hours after induction; nucleoids condense, the cytoplasm seems empty and the periplasmic space enlarges. The intracellular ATP level decreases about 27-fold suggesting the membrane potential may be disrupted.
      
 0.600
yfbR
5'-nucleotidase; Essential component of the deoxycytidine triphosphate (dCTP) pathway for de novo synthesis of thymidylate. Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates (dAMP, dGMP, dTMP, dUMP, dIMP and dCMP) and does not dephosphorylate 5'-ribonucleotides or ribonucleoside 3'-monophosphates.
      
 0.555
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.