node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cysD | cysE | b2752 | b3607 | ATP:sulfurylase (ATP:sulfate adenylyltransferase), subunit 2; Protein involved in sulfur metabolic process; Belongs to the PAPS reductase family. CysD subfamily. | Serine acetyltransferase; Protein involved in cysteine biosynthetic process; Belongs to the transferase hexapeptide repeat family. | 0.526 |
cysD | cysH | b2752 | b2762 | ATP:sulfurylase (ATP:sulfate adenylyltransferase), subunit 2; Protein involved in sulfur metabolic process; Belongs to the PAPS reductase family. CysD subfamily. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.989 |
cysD | cysI | b2752 | b2763 | ATP:sulfurylase (ATP:sulfate adenylyltransferase), subunit 2; Protein involved in sulfur metabolic process; Belongs to the PAPS reductase family. CysD subfamily. | Sulfite reductase, beta subunit, NAD(P)-binding, heme-binding; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.999 |
cysD | cysJ | b2752 | b2764 | ATP:sulfurylase (ATP:sulfate adenylyltransferase), subunit 2; Protein involved in sulfur metabolic process; Belongs to the PAPS reductase family. CysD subfamily. | Sulfite reductase, alpha subunit, flavoprotein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; In the N-terminal section; belongs to the flavodoxin family. | 0.999 |
cysD | cysK | b2752 | b2414 | ATP:sulfurylase (ATP:sulfate adenylyltransferase), subunit 2; Protein involved in sulfur metabolic process; Belongs to the PAPS reductase family. CysD subfamily. | Cysteine synthase A, O-acetylserine sulfhydrolase A subunit; (Microbial infection) In addition to its role in cysteine synthesis, stimulates the tRNase activity of CdiA-CT from E.coli strain 536 / UPEC; stimulation does not require O-acetylserine sulfhydrylase activity. CdiA is the toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion (experiments done in strains BW25113 [...] | 0.986 |
cysD | cysN | b2752 | b2751 | ATP:sulfurylase (ATP:sulfate adenylyltransferase), subunit 2; Protein involved in sulfur metabolic process; Belongs to the PAPS reductase family. CysD subfamily. | Sulfate adenylyltransferase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. | 0.999 |
cysD | cysP | b2752 | b2425 | ATP:sulfurylase (ATP:sulfate adenylyltransferase), subunit 2; Protein involved in sulfur metabolic process; Belongs to the PAPS reductase family. CysD subfamily. | Thiosulfate-binding protein; Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. This protein specifically binds thiosulfate and is involved in its transmembrane transport. | 0.999 |
cysD | metB | b2752 | b3939 | ATP:sulfurylase (ATP:sulfate adenylyltransferase), subunit 2; Protein involved in sulfur metabolic process; Belongs to the PAPS reductase family. CysD subfamily. | Cystathionine gamma-synthase, PLP-dependent; Catalyzes the formation of L-cystathionine from O-succinyl-L- homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2- oxobutanoate, succinate and ammonia. | 0.565 |
cysE | cysD | b3607 | b2752 | Serine acetyltransferase; Protein involved in cysteine biosynthetic process; Belongs to the transferase hexapeptide repeat family. | ATP:sulfurylase (ATP:sulfate adenylyltransferase), subunit 2; Protein involved in sulfur metabolic process; Belongs to the PAPS reductase family. CysD subfamily. | 0.526 |
cysE | cysH | b3607 | b2762 | Serine acetyltransferase; Protein involved in cysteine biosynthetic process; Belongs to the transferase hexapeptide repeat family. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.582 |
cysE | cysI | b3607 | b2763 | Serine acetyltransferase; Protein involved in cysteine biosynthetic process; Belongs to the transferase hexapeptide repeat family. | Sulfite reductase, beta subunit, NAD(P)-binding, heme-binding; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.482 |
cysE | cysK | b3607 | b2414 | Serine acetyltransferase; Protein involved in cysteine biosynthetic process; Belongs to the transferase hexapeptide repeat family. | Cysteine synthase A, O-acetylserine sulfhydrolase A subunit; (Microbial infection) In addition to its role in cysteine synthesis, stimulates the tRNase activity of CdiA-CT from E.coli strain 536 / UPEC; stimulation does not require O-acetylserine sulfhydrylase activity. CdiA is the toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion (experiments done in strains BW25113 [...] | 0.999 |
cysE | cysN | b3607 | b2751 | Serine acetyltransferase; Protein involved in cysteine biosynthetic process; Belongs to the transferase hexapeptide repeat family. | Sulfate adenylyltransferase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. | 0.420 |
cysE | metB | b3607 | b3939 | Serine acetyltransferase; Protein involved in cysteine biosynthetic process; Belongs to the transferase hexapeptide repeat family. | Cystathionine gamma-synthase, PLP-dependent; Catalyzes the formation of L-cystathionine from O-succinyl-L- homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2- oxobutanoate, succinate and ammonia. | 0.705 |
cysE | metC | b3607 | b3008 | Serine acetyltransferase; Protein involved in cysteine biosynthetic process; Belongs to the transferase hexapeptide repeat family. | Cystathionine beta-lyase, PLP-dependent; Primarily catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. Also exhibits cysteine desulfhydrase activity, producing sulfide from cysteine. In addition, under certain growth conditions, exhibits significant alanine racemase coactivity. | 0.571 |
cysH | cysD | b2762 | b2752 | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | ATP:sulfurylase (ATP:sulfate adenylyltransferase), subunit 2; Protein involved in sulfur metabolic process; Belongs to the PAPS reductase family. CysD subfamily. | 0.989 |
cysH | cysE | b2762 | b3607 | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | Serine acetyltransferase; Protein involved in cysteine biosynthetic process; Belongs to the transferase hexapeptide repeat family. | 0.582 |
cysH | cysI | b2762 | b2763 | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | Sulfite reductase, beta subunit, NAD(P)-binding, heme-binding; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.999 |
cysH | cysJ | b2762 | b2764 | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | Sulfite reductase, alpha subunit, flavoprotein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; In the N-terminal section; belongs to the flavodoxin family. | 0.999 |
cysH | cysK | b2762 | b2414 | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | Cysteine synthase A, O-acetylserine sulfhydrolase A subunit; (Microbial infection) In addition to its role in cysteine synthesis, stimulates the tRNase activity of CdiA-CT from E.coli strain 536 / UPEC; stimulation does not require O-acetylserine sulfhydrylase activity. CdiA is the toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion (experiments done in strains BW25113 [...] | 0.977 |