Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
query proteins and first shell of interactors
second shell of interactors
proteins of unknown 3D structure
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
|cysM||Two cysteine synthase enzymes are found. Both catalyze the same reaction. Cysteine synthase B can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product (303 aa)|| |
Predicted Functional Partners:
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
| || || || ||0.992
Belongs to the transferase hexapeptide repeat family.
| || || ||0.992
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component
| || || ||0.988
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system
| || || ||0.984
Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane
| || || || ||0.964
Reduction of activated sulfate into sulfite
| || || || ||0.938
Catalyzes the synthesis of activated sulfate
| || || || || ||0.934
Belongs to the PAPS reductase family. CysD subfamily.
| || || || ||0.931
May be the GTPase, regulating ATP sulfurylase activity
| || || || || ||0.907
Primarily catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis . Also exhibits cysteine desulfhydrase activity, producing sulfide from cysteine . In addition, under certain growth conditions, exhibits significant alanine racemase coactivity
| || ||0.901
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (3%) [HD]