STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfgOPutative upf0118 family inner membrane permease; Putative permease (353 aa)    
Predicted Functional Partners:
bepA
Om protein maintenance and assembly metalloprotease and chaperone, periplasmic; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. Promotes disulfide rearrangement of LptD during its biogenesis, and proteolytic degradation of LptD and BamA when their proper assembly is compromised. May facilitate membrane attachment of LoiP under unfavorable conditions
     
 0.740
ybhP
Endonuclease/exonuclease/phosphatase domain-containing protein ybhp; Uncharacterized protein YbhP; Protein involved in DNA catabolic process
     
 0.730
ydiK
annotation not available
      
 0.641
ymfQ
E14 prophage; conserved protein YmfQ; To phage Mu protein gp48 and H.influenzae HI_1521
      
 0.640
ydcT
Putative spermidine/putrescine transport system atp-binding protein; Probably part of the ABC transporter complex YdcSTUV. Probably responsible for energy coupling to the transport system
      
 0.607
yfdK
CPS-53 (KpLE1) prophage; putative tail fiber assembly protein YfdK; To E.coli YmfS
      
 0.607
yhgN
annotation not available
      
 0.590
hyfJ
Putative processing element hydrogenase 4; Possible component of hydrogenase 4
      
 0.560
yfgD
Arsenate reductase (glutaredoxin); Belongs to the ArsC family
     
 0.537
stfP
Uncharacterized protein StfP; Phage or Prophage Related; To E.coli YfdL and M.jannaschii MJ0347
      
 0.520
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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