STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfgGannotation not available (63 aa)    
Predicted Functional Partners:
insL1
IS186/IS421 transposase; IS, phage, Tn; Transposon-related functions; extrachromosomal; transposon related
  
   
 0.841
b0582
IS186 transposase; IS, phage, Tn; Transposon-related functions; extrachromosomal; transposon related
  
   
 0.841
b2394
annotation not available
  
   
 0.841
yfgF
Cyclic-di-gmp phosphodiesterase, anaerobic; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic-di-GMP (c-di-GMP) to 5'-pGpG. Truncated proteins consisting of the GGDEF/EAL domains (residues 319-747) or of the EAL domain alone (481-747) have c-di-GMP phosphodiesterase activity. They do not have diguanylate cyclase activity. Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria
     
 0.813
ybjE
Putative transporter; Mediates export of lysine
      
 0.641
yjtD
Putative rrna methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
  
   
 0.627
yfeX
Porphyrinogen oxidase, cytoplasmic; Has both general peroxidase activity and dye-decolorizing activity. Can catalyze the oxidation of both protoporphyrinogen IX and coproporphyrinogen III to their corresponding porphyrins. Also efficiently decolorizes the dyes alizarin red and Cibacron blue F3GA
  
   
 0.622
ydjX
TVP38/TMEM64 family inner membrane protein; Belongs to the TVP38/TMEM64 family
      
 0.619
ygeH
Transcriptional regulator hila, main transcriptional regulator of spi1; Uncharacterized protein YgeH; Putative invasion protein
      
 0.605
yjhB
Putative mfs transporter, membrane protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
      
 0.605
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.