STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yphBannotation not available (290 aa)    
Predicted Functional Partners:
yphC
Uncharacterized zinc-type alcohol dehydrogenase-like protein YphC; Putative oxidoreductase
 
    0.875
yihQ
Catalyzes the hydrolysis of sulfoquinovosyl diacylglycerides (SQDG) to sulfoquinovose (SQ), which is then degraded by E.coli through the SQ Embden-Meyerhof-Parnas (SQ-EMP) sulfoglycolysis pathway as a source of carbon and sulfur. Therefore, is likely involved in the utilization of the sulfoquinovose headgroup found in ubiquitous plant sulfolipids. Is also able to hydrolyze simple sulfoquinovosides such as 1-sulfoquinovosylglycerol (SQGro). Is a retaining glycoside hydrolase, since it forms the alpha anomer of SQ . Also exhibits some alpha-glucosidase activity against alpha-glucosyl flu [...]
     
 0.814
yphF
Probably part of the binding-protein-dependent transport system YphDEF
 
     0.747
yphD
Probably part of the binding-protein-dependent transport system YphDEF. Probably responsible for the translocation of the substrate across the membrane
       0.658
yphE
Probably part of a binding-protein-dependent transport system YphDEF. Probably responsible for energy coupling to the transport system
 
     0.653
yphG
annotation not available
 
    0.635
ydhQ
Uncharacterized protein YdhQ; Possible enzyme
  
     0.624
mdtO
Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride
  
     0.620
yphH
Belongs to the ROK (NagC/XylR) family
 
   
 0.604
xylR
Regulatory protein for the xylBAFGHR operon
     
 0.596
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (4%) [HD]