STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yphDProbably part of the binding-protein-dependent transport system YphDEF. Probably responsible for the translocation of the substrate across the membrane (332 aa)    
Predicted Functional Partners:
yphE
Probably part of a binding-protein-dependent transport system YphDEF. Probably responsible for energy coupling to the transport system
   
 0.948
yphF
Probably part of the binding-protein-dependent transport system YphDEF
 
   
 0.927
rbsB
Part of the ABC transporter complex RbsABC involved in ribose import. Binds ribose. Also serves as the primary chemoreceptor for chemotaxis
 
   
 0.789
rbsA
Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system.
 
   
 0.780
alsA
Part of the ABC transporter complex AlsBAC involved in D- allose import. Probably responsible for energy coupling to the transport system
 
   
 0.776
alsB
Part of the binding-protein-dependent transport system AlsBAC for D-allose
 
   
 0.775
araG
Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system (Probable)
 
   
 0.772
xylG
Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system (Probable). The XylFGH system can also transport ribose in absence of xylose
 
   
 0.750
mglA
Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system (Probable)
 
   
 0.748
ytfR
Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable). Responsible for energy coupling to the transport system (Probable)
 
   
 0.729
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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