node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
eamA | eamB | b1533 | b2578 | Cysteine and O-acetyl-L-serine efflux system; May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O-acetyl-L- serine (OAS)), and for other amino acids and their metabolites. Belongs to the EamA transporter family. | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. | 0.811 |
eamA | rhtC | b1533 | b3823 | Cysteine and O-acetyl-L-serine efflux system; May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O-acetyl-L- serine (OAS)), and for other amino acids and their metabolites. Belongs to the EamA transporter family. | Threonine efflux pump; Conducts the efflux of threonine. Belongs to the Rht family. | 0.465 |
eamB | eamA | b2578 | b1533 | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. | Cysteine and O-acetyl-L-serine efflux system; May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O-acetyl-L- serine (OAS)), and for other amino acids and their metabolites. Belongs to the EamA transporter family. | 0.811 |
eamB | fadK | b2578 | b1701 | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. | Short chain acyl-CoA synthetase, anaerobic; Catalyzes the esterification, concomitant with transport, of exogenous fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. Is maximally active on C6:0, C8:0 and C12:0 fatty acids, while has a low activity on C14-C18 chain length fatty acids. Is involved in the anaerobic beta-oxidative degradation of fatty acids, which allows anaerobic growth of E.coli on fatty acids as a sole carbon and energy source in the presence of nitrate or fumarate as a terminal electron acceptor. Can fun [...] | 0.429 |
eamB | leuE | b2578 | b1798 | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. | Leucine efflux protein; Exporter of leucine. Can also transport its natural analog L- alpha-amino-n-butyric acid and some other structurally unrelated amino acids. | 0.692 |
eamB | lplT | b2578 | b2835 | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. | Lysophospholipid transporter; Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell. Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family. | 0.509 |
eamB | rhtC | b2578 | b3823 | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. | Threonine efflux pump; Conducts the efflux of threonine. Belongs to the Rht family. | 0.485 |
eamB | tehA | b2578 | b1429 | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. | Potassium-tellurite ethidium and proflavin transporter; Responsible for potassium tellurite resistance when present in high copy number. Ion channel involved in potassium tellurite resistance (By similarity). Otherwise, phenotypically silent. Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family. | 0.529 |
eamB | ybaO | b2578 | b0447 | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. | Putative DNA-binding transcriptional regulator; Plays a role in L-cysteine detoxification. Binds to the dlsT(yhaO)-yhaM operon promoter in the presence but not absence of L- cysteine; activates transcription from the dlsT(yhaO)-yhaM operon. No other DNA target was identified in strain K12 / BW25113. Thiosulfate does not activate its transcription function. Overexpression doubles hydrogen sulfide production in the presence of cysteine. | 0.412 |
eamB | yeaY | b2578 | b1806 | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. | Slp family lipoprotein, RpoE-regulated; Putative outer membrane protein. | 0.496 |
eamB | yfiE | b2578 | b2577 | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. | Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. | 0.620 |
eamB | yicG | b2578 | b3646 | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. | UPF0126 family inner membrane protein. | 0.670 |
fadK | eamB | b1701 | b2578 | Short chain acyl-CoA synthetase, anaerobic; Catalyzes the esterification, concomitant with transport, of exogenous fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. Is maximally active on C6:0, C8:0 and C12:0 fatty acids, while has a low activity on C14-C18 chain length fatty acids. Is involved in the anaerobic beta-oxidative degradation of fatty acids, which allows anaerobic growth of E.coli on fatty acids as a sole carbon and energy source in the presence of nitrate or fumarate as a terminal electron acceptor. Can fun [...] | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. | 0.429 |
fadK | lplT | b1701 | b2835 | Short chain acyl-CoA synthetase, anaerobic; Catalyzes the esterification, concomitant with transport, of exogenous fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. Is maximally active on C6:0, C8:0 and C12:0 fatty acids, while has a low activity on C14-C18 chain length fatty acids. Is involved in the anaerobic beta-oxidative degradation of fatty acids, which allows anaerobic growth of E.coli on fatty acids as a sole carbon and energy source in the presence of nitrate or fumarate as a terminal electron acceptor. Can fun [...] | Lysophospholipid transporter; Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell. Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family. | 0.488 |
fadK | yeaY | b1701 | b1806 | Short chain acyl-CoA synthetase, anaerobic; Catalyzes the esterification, concomitant with transport, of exogenous fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. Is maximally active on C6:0, C8:0 and C12:0 fatty acids, while has a low activity on C14-C18 chain length fatty acids. Is involved in the anaerobic beta-oxidative degradation of fatty acids, which allows anaerobic growth of E.coli on fatty acids as a sole carbon and energy source in the presence of nitrate or fumarate as a terminal electron acceptor. Can fun [...] | Slp family lipoprotein, RpoE-regulated; Putative outer membrane protein. | 0.438 |
fadK | yicG | b1701 | b3646 | Short chain acyl-CoA synthetase, anaerobic; Catalyzes the esterification, concomitant with transport, of exogenous fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. Is maximally active on C6:0, C8:0 and C12:0 fatty acids, while has a low activity on C14-C18 chain length fatty acids. Is involved in the anaerobic beta-oxidative degradation of fatty acids, which allows anaerobic growth of E.coli on fatty acids as a sole carbon and energy source in the presence of nitrate or fumarate as a terminal electron acceptor. Can fun [...] | UPF0126 family inner membrane protein. | 0.561 |
leuE | eamB | b1798 | b2578 | Leucine efflux protein; Exporter of leucine. Can also transport its natural analog L- alpha-amino-n-butyric acid and some other structurally unrelated amino acids. | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. | 0.692 |
leuE | rhtC | b1798 | b3823 | Leucine efflux protein; Exporter of leucine. Can also transport its natural analog L- alpha-amino-n-butyric acid and some other structurally unrelated amino acids. | Threonine efflux pump; Conducts the efflux of threonine. Belongs to the Rht family. | 0.500 |
lplT | eamB | b2835 | b2578 | Lysophospholipid transporter; Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell. Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family. | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. | 0.509 |
lplT | fadK | b2835 | b1701 | Lysophospholipid transporter; Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell. Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family. | Short chain acyl-CoA synthetase, anaerobic; Catalyzes the esterification, concomitant with transport, of exogenous fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. Is maximally active on C6:0, C8:0 and C12:0 fatty acids, while has a low activity on C14-C18 chain length fatty acids. Is involved in the anaerobic beta-oxidative degradation of fatty acids, which allows anaerobic growth of E.coli on fatty acids as a sole carbon and energy source in the presence of nitrate or fumarate as a terminal electron acceptor. Can fun [...] | 0.488 |