STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfiPannotation not available (232 aa)    
Predicted Functional Partners:
yagA
Uncharacterized protein YagA; Pseudogene, CP4-6 prophage;Phage or Prophage Related
      
 0.920
pka
Peptidyl-lysine acetyltransferase; Catalyzes the acetyl-CoA-dependent acetylation of lysine residues of a large number of target proteins. Acetylates RNase R in exponential phase cells and RNase II Required for the glucose-dependent acetylation on multiple lysines of alpha, beta and beta' RNAP subunits . Also acetylates acetyl-coenzyme A synthetase (Acs) and the chromosomal replication initiator protein DnaA, and inhibits their activity . Overexpression leads to the acetylation of a large number of additional proteins and inhibits motility
       0.813
yfcA
Taue/tsup family inner membrane protein; Probable membrane transporter protein YfcA; Putative structural protein
  
  
 0.746
yaeF
annotation not available
 
      0.742
yaiI
annotation not available
   
  
 0.737
rarD
Putative chloramphenical resistance permease; Protein involved in response to drug and chloramphenicol transport
      
 0.672
yhhN
TMEM86 family putative inner membrane protein; Uncharacterized membrane protein YhhN; Putative enzyme
      
 0.671
trxC
Reduced thioredoxin 2; Efficient electron donor for the essential enzyme ribonucleotide reductase. Is also able to reduce the interchain disulfide bridges of insulin
       0.633
pssA
CDP-diacylglycerol--serine O-phosphatidyltransferase; Phosphatidylserine synthase; phospholipid synthesis; Protein involved in phospholipid biosynthetic process
  
    0.524
ygdD
annotation not available
      
 0.520
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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