node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
rimM | rplS | b2608 | b2606 | One of at least 4 proteins (Era, RbfA, RimM and RsgA/YjeQ) that assist in the late assembly stage of the 30S ribosomal subunit. An accessory protein needed during the final step in assembly of the 30S ribosomal subunit, for assembly of the head region (the 16S rRNA 3' domain) It may act while Era is associated and before RimP in 30S subunit assembly . Interacts with S19 . Essential for efficient processing of 16S rRNA; a deletion mutant accumulates 17S rRNA . Deletions also do not assemble the head-associated ribosomal proteins correctly . May be needed both before and after RbfA durin [...] | This protein is located at the 30S-50S ribosomal subunit interface. In the 70S ribosome it has been modeled to make two contacts with the 16S rRNA of the 30S subunit forming part of bridges B6 and B8 . In the 3.5 A resolved structures L14 and L19 interact and together make contact with the 16S rRNA . The protein conformation is quite different between the 50S and 70S structures, which may be necessary for translocation | 0.972 |
rimM | rpoA | b2608 | b3295 | One of at least 4 proteins (Era, RbfA, RimM and RsgA/YjeQ) that assist in the late assembly stage of the 30S ribosomal subunit. An accessory protein needed during the final step in assembly of the 30S ribosomal subunit, for assembly of the head region (the 16S rRNA 3' domain) It may act while Era is associated and before RimP in 30S subunit assembly . Interacts with S19 . Essential for efficient processing of 16S rRNA; a deletion mutant accumulates 17S rRNA . Deletions also do not assemble the head-associated ribosomal proteins correctly . May be needed both before and after RbfA durin [...] | Dna-directed rna polymerase subunit alpha; DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme | 0.908 |
rimM | rpoB | b2608 | b3987 | One of at least 4 proteins (Era, RbfA, RimM and RsgA/YjeQ) that assist in the late assembly stage of the 30S ribosomal subunit. An accessory protein needed during the final step in assembly of the 30S ribosomal subunit, for assembly of the head region (the 16S rRNA 3' domain) It may act while Era is associated and before RimP in 30S subunit assembly . Interacts with S19 . Essential for efficient processing of 16S rRNA; a deletion mutant accumulates 17S rRNA . Deletions also do not assemble the head-associated ribosomal proteins correctly . May be needed both before and after RbfA durin [...] | Dna-directed rna polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates | 0.842 |
rimM | rpsB | b2608 | b0169 | One of at least 4 proteins (Era, RbfA, RimM and RsgA/YjeQ) that assist in the late assembly stage of the 30S ribosomal subunit. An accessory protein needed during the final step in assembly of the 30S ribosomal subunit, for assembly of the head region (the 16S rRNA 3' domain) It may act while Era is associated and before RimP in 30S subunit assembly . Interacts with S19 . Essential for efficient processing of 16S rRNA; a deletion mutant accumulates 17S rRNA . Deletions also do not assemble the head-associated ribosomal proteins correctly . May be needed both before and after RbfA durin [...] | Small subunit ribosomal protein s2; Required for ribosomal protein S1 to bind to the 30S subunit | 0.841 |
rimM | rpsD | b2608 | b3296 | One of at least 4 proteins (Era, RbfA, RimM and RsgA/YjeQ) that assist in the late assembly stage of the 30S ribosomal subunit. An accessory protein needed during the final step in assembly of the 30S ribosomal subunit, for assembly of the head region (the 16S rRNA 3' domain) It may act while Era is associated and before RimP in 30S subunit assembly . Interacts with S19 . Essential for efficient processing of 16S rRNA; a deletion mutant accumulates 17S rRNA . Deletions also do not assemble the head-associated ribosomal proteins correctly . May be needed both before and after RbfA durin [...] | Small subunit ribosomal protein s4; One of two assembly initiator proteins for the 30S subunit, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. Plays a role in mRNA unwinding by the ribosome, possibly by forming part of a processivity clamp. Also functions as a rho-dependent antiterminator of rRNA transcription, increasing the synthesis of rRNA under conditions of excess protein, allowing a more rapid return to homeostasis. Binds directly to RNA polymerase | 0.864 |
rimM | rpsH | b2608 | b3306 | One of at least 4 proteins (Era, RbfA, RimM and RsgA/YjeQ) that assist in the late assembly stage of the 30S ribosomal subunit. An accessory protein needed during the final step in assembly of the 30S ribosomal subunit, for assembly of the head region (the 16S rRNA 3' domain) It may act while Era is associated and before RimP in 30S subunit assembly . Interacts with S19 . Essential for efficient processing of 16S rRNA; a deletion mutant accumulates 17S rRNA . Deletions also do not assemble the head-associated ribosomal proteins correctly . May be needed both before and after RbfA durin [...] | Small subunit ribosomal protein s8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit | 0.898 |
rimM | rpsP | b2608 | b2609 | One of at least 4 proteins (Era, RbfA, RimM and RsgA/YjeQ) that assist in the late assembly stage of the 30S ribosomal subunit. An accessory protein needed during the final step in assembly of the 30S ribosomal subunit, for assembly of the head region (the 16S rRNA 3' domain) It may act while Era is associated and before RimP in 30S subunit assembly . Interacts with S19 . Essential for efficient processing of 16S rRNA; a deletion mutant accumulates 17S rRNA . Deletions also do not assemble the head-associated ribosomal proteins correctly . May be needed both before and after RbfA durin [...] | Small subunit ribosomal protein s16; In addition to being a ribosomal protein, S16 also has a cation-dependent endonuclease activity | 0.999 |
rimM | trmD | b2608 | b2607 | One of at least 4 proteins (Era, RbfA, RimM and RsgA/YjeQ) that assist in the late assembly stage of the 30S ribosomal subunit. An accessory protein needed during the final step in assembly of the 30S ribosomal subunit, for assembly of the head region (the 16S rRNA 3' domain) It may act while Era is associated and before RimP in 30S subunit assembly . Interacts with S19 . Essential for efficient processing of 16S rRNA; a deletion mutant accumulates 17S rRNA . Deletions also do not assemble the head-associated ribosomal proteins correctly . May be needed both before and after RbfA durin [...] | Trna m(1)g37 methyltransferase, sam-dependent; Specifically methylates guanosine-37 in various tRNAs | 0.999 |
rplS | rimM | b2606 | b2608 | This protein is located at the 30S-50S ribosomal subunit interface. In the 70S ribosome it has been modeled to make two contacts with the 16S rRNA of the 30S subunit forming part of bridges B6 and B8 . In the 3.5 A resolved structures L14 and L19 interact and together make contact with the 16S rRNA . The protein conformation is quite different between the 50S and 70S structures, which may be necessary for translocation | One of at least 4 proteins (Era, RbfA, RimM and RsgA/YjeQ) that assist in the late assembly stage of the 30S ribosomal subunit. An accessory protein needed during the final step in assembly of the 30S ribosomal subunit, for assembly of the head region (the 16S rRNA 3' domain) It may act while Era is associated and before RimP in 30S subunit assembly . Interacts with S19 . Essential for efficient processing of 16S rRNA; a deletion mutant accumulates 17S rRNA . Deletions also do not assemble the head-associated ribosomal proteins correctly . May be needed both before and after RbfA durin [...] | 0.972 |
rplS | rpoA | b2606 | b3295 | This protein is located at the 30S-50S ribosomal subunit interface. In the 70S ribosome it has been modeled to make two contacts with the 16S rRNA of the 30S subunit forming part of bridges B6 and B8 . In the 3.5 A resolved structures L14 and L19 interact and together make contact with the 16S rRNA . The protein conformation is quite different between the 50S and 70S structures, which may be necessary for translocation | Dna-directed rna polymerase subunit alpha; DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme | 0.977 |
rplS | rpoB | b2606 | b3987 | This protein is located at the 30S-50S ribosomal subunit interface. In the 70S ribosome it has been modeled to make two contacts with the 16S rRNA of the 30S subunit forming part of bridges B6 and B8 . In the 3.5 A resolved structures L14 and L19 interact and together make contact with the 16S rRNA . The protein conformation is quite different between the 50S and 70S structures, which may be necessary for translocation | Dna-directed rna polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates | 0.992 |
rplS | rpsB | b2606 | b0169 | This protein is located at the 30S-50S ribosomal subunit interface. In the 70S ribosome it has been modeled to make two contacts with the 16S rRNA of the 30S subunit forming part of bridges B6 and B8 . In the 3.5 A resolved structures L14 and L19 interact and together make contact with the 16S rRNA . The protein conformation is quite different between the 50S and 70S structures, which may be necessary for translocation | Small subunit ribosomal protein s2; Required for ribosomal protein S1 to bind to the 30S subunit | 0.999 |
rplS | rpsD | b2606 | b3296 | This protein is located at the 30S-50S ribosomal subunit interface. In the 70S ribosome it has been modeled to make two contacts with the 16S rRNA of the 30S subunit forming part of bridges B6 and B8 . In the 3.5 A resolved structures L14 and L19 interact and together make contact with the 16S rRNA . The protein conformation is quite different between the 50S and 70S structures, which may be necessary for translocation | Small subunit ribosomal protein s4; One of two assembly initiator proteins for the 30S subunit, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. Plays a role in mRNA unwinding by the ribosome, possibly by forming part of a processivity clamp. Also functions as a rho-dependent antiterminator of rRNA transcription, increasing the synthesis of rRNA under conditions of excess protein, allowing a more rapid return to homeostasis. Binds directly to RNA polymerase | 0.999 |
rplS | rpsH | b2606 | b3306 | This protein is located at the 30S-50S ribosomal subunit interface. In the 70S ribosome it has been modeled to make two contacts with the 16S rRNA of the 30S subunit forming part of bridges B6 and B8 . In the 3.5 A resolved structures L14 and L19 interact and together make contact with the 16S rRNA . The protein conformation is quite different between the 50S and 70S structures, which may be necessary for translocation | Small subunit ribosomal protein s8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit | 0.999 |
rplS | rpsP | b2606 | b2609 | This protein is located at the 30S-50S ribosomal subunit interface. In the 70S ribosome it has been modeled to make two contacts with the 16S rRNA of the 30S subunit forming part of bridges B6 and B8 . In the 3.5 A resolved structures L14 and L19 interact and together make contact with the 16S rRNA . The protein conformation is quite different between the 50S and 70S structures, which may be necessary for translocation | Small subunit ribosomal protein s16; In addition to being a ribosomal protein, S16 also has a cation-dependent endonuclease activity | 0.999 |
rplS | trmD | b2606 | b2607 | This protein is located at the 30S-50S ribosomal subunit interface. In the 70S ribosome it has been modeled to make two contacts with the 16S rRNA of the 30S subunit forming part of bridges B6 and B8 . In the 3.5 A resolved structures L14 and L19 interact and together make contact with the 16S rRNA . The protein conformation is quite different between the 50S and 70S structures, which may be necessary for translocation | Trna m(1)g37 methyltransferase, sam-dependent; Specifically methylates guanosine-37 in various tRNAs | 0.997 |
rpoA | rimM | b3295 | b2608 | Dna-directed rna polymerase subunit alpha; DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme | One of at least 4 proteins (Era, RbfA, RimM and RsgA/YjeQ) that assist in the late assembly stage of the 30S ribosomal subunit. An accessory protein needed during the final step in assembly of the 30S ribosomal subunit, for assembly of the head region (the 16S rRNA 3' domain) It may act while Era is associated and before RimP in 30S subunit assembly . Interacts with S19 . Essential for efficient processing of 16S rRNA; a deletion mutant accumulates 17S rRNA . Deletions also do not assemble the head-associated ribosomal proteins correctly . May be needed both before and after RbfA durin [...] | 0.908 |
rpoA | rplS | b3295 | b2606 | Dna-directed rna polymerase subunit alpha; DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme | This protein is located at the 30S-50S ribosomal subunit interface. In the 70S ribosome it has been modeled to make two contacts with the 16S rRNA of the 30S subunit forming part of bridges B6 and B8 . In the 3.5 A resolved structures L14 and L19 interact and together make contact with the 16S rRNA . The protein conformation is quite different between the 50S and 70S structures, which may be necessary for translocation | 0.977 |
rpoA | rpoB | b3295 | b3987 | Dna-directed rna polymerase subunit alpha; DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme | Dna-directed rna polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates | 0.999 |
rpoA | rpsB | b3295 | b0169 | Dna-directed rna polymerase subunit alpha; DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme | Small subunit ribosomal protein s2; Required for ribosomal protein S1 to bind to the 30S subunit | 0.998 |