STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfjQUPF0380 protein YfjQ; Phage or Prophage Related; Belongs to the UPF0380 family (273 aa)    
Predicted Functional Partners:
yfjP
Uncharacterized protein YfjP; Putative GTP-binding protein; To E.coli YkfA and YeeP
 
    0.909
yfjR
Uncharacterized HTH-type transcriptional regulator YfjR; Phage or Prophage Related
 
    0.860
yfjX
Uncharacterized protein YfjX; Pseudogene, CP4-57 putative prophage remnant;Phage or Prophage Related; Belongs to the antirestriction protein family
 
    0.801
yafX
Uncharacterized protein YafX; Phage or Prophage Related; Belongs to the antirestriction protein family
 
     0.776
ykfA
Uncharacterized protein YkfA; Putative GTP-binding protein; To E.coli YfjP and YeeP
 
     0.771
yfjZ
Putative antitoxin YfjZ; Might be an antitoxin component of a type II toxin- antitoxin (TA) system. A putative antitoxin that may inactivate probable toxin YpjF (Potential)
 
    0.751
ykfH
annotation not available
 
     0.747
ypjF
Probable toxin YpjF; Toxic component of a type II toxin-antitoxin (TA) system. Overexpression results in inhibition of growth in liquid cultures. Might be inactivated by putative antitoxin YfjZ
  
     0.745
cbtA
Cytoskeleton-binding toxin CbtA; Toxic component of a type IV toxin-antitoxin (TA) system. Interacts with cytoskeletal proteins FtsZ and MreB; inhibits FtsZ GTP-dependent polymerization and GTPase activity as well as MreB ATP-dependent polymerization. Binds to both the N- and C-terminus of FtsZ, likely blocking its polymerization. Overexpression results in inhibition of growth in liquid cultures and decrease in colony formation; these effects are overcome by concomitant expression of antitoxin CbeA (YeeU). In other experiments after 6 hours cells are lemon-shaped and by 24 hours those [...]
  
     0.744
ypjJ
annotation not available
  
     0.744
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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