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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yqaEannotation not available (52 aa)    
Predicted Functional Partners:
yhcC
Putative fe-s oxidoreductase, radical sam superfamily protein; In vitro, can cleave S-adenosyl-L-methionine into methionine and 5'-deoxyadenosine (AdoH)
      
 0.813
chaB
Putative cation transport regulator chab; Might be a regulator of the sodium-potassium/proton antiporter ChaA
      
 0.730
ygaU
Uncharacterized protein; Highly specific potassium binding protein that is required for normal growth in the presence of high levels of external K(+). May act as a sensor of cytoplasmic K(+) concentration. Binds a single K(+) ion, which induces a large conformational change. Can also bind the larger alkali metal ions Rb(+) and Cs(+), and NH(4)(+) . May be involved in the regulation of peptidoglycan cross-linking
  
    0.703
yoeI
annotation not available
      
 0.678
yncJ
annotation not available
      
 0.619
ygaV
Putative dna-binding transcriptional regulator ygav; Functions as transcription repressor
       0.575
osmB
Osmotically and stress inducible lipoprotein; Provides resistance to osmotic stress. May be important for stationary-phase survival
   
  
 0.568
nadE
Nad synthetase, nh3/glutamine-dependent; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
      
 0.561
ygaP
annotation not available
       0.538
wcaC
Putative colanic acid biosynthesis glycosyl transferase WcaC; Protein involved in colanic acid biosynthetic process
      
 0.512
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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