node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
birA | ygaV | b3973 | b2667 | Bira family transcriptional regulator, biotin operon repressor / biotin---[acetyl-coa-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon | Putative dna-binding transcriptional regulator ygav; Functions as transcription repressor | 0.508 |
damX | ygaV | b3388 | b2667 | Cell division protein that binds to the septal ring; Non-essential cell division protein | Putative dna-binding transcriptional regulator ygav; Functions as transcription repressor | 0.418 |
pbpG | ygaV | b2134 | b2667 | Serine-type d-ala-d-ala endopeptidase (penicillin-binding protein 7); Cell wall formation. May play a specialized role in remodeling the cell wall. Specifically hydrolyzes the DD- diaminopimelate-alanine bonds in high-molecular-mass murein sacculi | Putative dna-binding transcriptional regulator ygav; Functions as transcription repressor | 0.414 |
pspD | pspG | b1307 | b4050 | Peripheral inner membrane phage-shock protein; The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions | Phage shock protein g; Effector of the phage shock response | 0.641 |
pspD | yejG | b1307 | b2181 | Peripheral inner membrane phage-shock protein; The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions | annotation not available | 0.479 |
pspD | ygaV | b1307 | b2667 | Peripheral inner membrane phage-shock protein; The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions | Putative dna-binding transcriptional regulator ygav; Functions as transcription repressor | 0.499 |
pspG | pspD | b4050 | b1307 | Phage shock protein g; Effector of the phage shock response | Peripheral inner membrane phage-shock protein; The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions | 0.641 |
pspG | yejG | b4050 | b2181 | Phage shock protein g; Effector of the phage shock response | annotation not available | 0.620 |
pspG | ygaV | b4050 | b2667 | Phage shock protein g; Effector of the phage shock response | Putative dna-binding transcriptional regulator ygav; Functions as transcription repressor | 0.474 |
rcnR | ygaV | b2105 | b2667 | Frmr/rcnr family transcriptional regulator, repressor of rcna expression; Repressor of rcnA expression. Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt. In the presence of one of these metals, it has a weaker affinity for rcnA promoter | Putative dna-binding transcriptional regulator ygav; Functions as transcription repressor | 0.432 |
yejG | pspD | b2181 | b1307 | annotation not available | Peripheral inner membrane phage-shock protein; The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions | 0.479 |
yejG | pspG | b2181 | b4050 | annotation not available | Phage shock protein g; Effector of the phage shock response | 0.620 |
yejG | ygaV | b2181 | b2667 | annotation not available | Putative dna-binding transcriptional regulator ygav; Functions as transcription repressor | 0.730 |
ygaP | ygaU | b2668 | b2665 | annotation not available | Uncharacterized protein; Highly specific potassium binding protein that is required for normal growth in the presence of high levels of external K(+). May act as a sensor of cytoplasmic K(+) concentration. Binds a single K(+) ion, which induces a large conformational change. Can also bind the larger alkali metal ions Rb(+) and Cs(+), and NH(4)(+) . May be involved in the regulation of peptidoglycan cross-linking | 0.401 |
ygaP | ygaV | b2668 | b2667 | annotation not available | Putative dna-binding transcriptional regulator ygav; Functions as transcription repressor | 0.994 |
ygaP | yqaE | b2668 | b2666 | annotation not available | annotation not available | 0.538 |
ygaU | ygaP | b2665 | b2668 | Uncharacterized protein; Highly specific potassium binding protein that is required for normal growth in the presence of high levels of external K(+). May act as a sensor of cytoplasmic K(+) concentration. Binds a single K(+) ion, which induces a large conformational change. Can also bind the larger alkali metal ions Rb(+) and Cs(+), and NH(4)(+) . May be involved in the regulation of peptidoglycan cross-linking | annotation not available | 0.401 |
ygaU | ygaV | b2665 | b2667 | Uncharacterized protein; Highly specific potassium binding protein that is required for normal growth in the presence of high levels of external K(+). May act as a sensor of cytoplasmic K(+) concentration. Binds a single K(+) ion, which induces a large conformational change. Can also bind the larger alkali metal ions Rb(+) and Cs(+), and NH(4)(+) . May be involved in the regulation of peptidoglycan cross-linking | Putative dna-binding transcriptional regulator ygav; Functions as transcription repressor | 0.405 |
ygaU | yqaE | b2665 | b2666 | Uncharacterized protein; Highly specific potassium binding protein that is required for normal growth in the presence of high levels of external K(+). May act as a sensor of cytoplasmic K(+) concentration. Binds a single K(+) ion, which induces a large conformational change. Can also bind the larger alkali metal ions Rb(+) and Cs(+), and NH(4)(+) . May be involved in the regulation of peptidoglycan cross-linking | annotation not available | 0.703 |
ygaV | birA | b2667 | b3973 | Putative dna-binding transcriptional regulator ygav; Functions as transcription repressor | Bira family transcriptional regulator, biotin operon repressor / biotin---[acetyl-coa-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon | 0.508 |