STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alaEAlanine exporter, alanine-inducible, stress-responsive; Exports L-alanine (149 aa)    
Predicted Functional Partners:
ytfF
Dmt transporter family inner membrane protein; Inner membrane protein YtfF; Putative transmembrane subunit
  
   
 0.889
yhcC
Putative fe-s oxidoreductase, radical sam superfamily protein; In vitro, can cleave S-adenosyl-L-methionine into methionine and 5'-deoxyadenosine (AdoH)
  
   
 0.859
leuE
Leucine efflux protein; Exporter of leucine. Can also transport its natural analog L- alpha-amino-n-butyric acid and some other structurally unrelated amino acids
      
 0.830
yddG
Aromatic amino acid exporter; Probable efflux pump. Overexpression confers resistance to phenylalanine and increases export of phenylalanine, tyrosine and tryptophan
  
   
 0.808
dadA
D-amino-acid dehydrogenase; Catalyzes the oxidative deamination of D-amino acids. Has broad substrate specificity; is mostly active on D-alanine, and to a lesser extent, on several other D-amino acids such as D-methionine, D- serine and D-proline, but not on L-alanine. Participates in the utilization of L-alanine and D-alanine as the sole source of carbon, nitrogen and energy for growth. Is also able to oxidize D-amino acid analogs such as 3,4-dehydro-D-proline, D-2-aminobutyrate, D-norvaline, D-norleucine, cis-4-hydroxy-D-proline, and DL-ethionine
      
 0.742
yoeI
annotation not available
      
 0.679
yjeT
annotation not available
  
     0.624
dadX
Alanine racemase, catabolic, plp-binding; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA
      
 0.620
uspB
Putative universal stress (ethanol tolerance) protein b; Belongs to the universal stress protein B family
  
   
 0.542
ytfB
Cell division protein ytfb; Cell division protein whose function is related to the generation of a transient cell wall structure. Function is linked to the late stages of cell division
  
     0.518
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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