STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proXGlycine betaine/proline abc transporter periplasmic binding protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Binds glycine betaine and proline betaine with high affinity (330 aa)    
Predicted Functional Partners:
proV
Glycine betaine/proline abc transporter periplasmic binding protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake Probably responsible for energy coupling to the transport system (Probable)
 
 0.999
proW
Glycine betaine/proline transport system permease protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake Probably responsible for the translocation of the substrate across the membrane (Probable)
 
 0.999
yccS
annotation not available
      
 0.640
proP
Mfs transporter, mhs family, proline/betaine transporter; Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response
      
 0.609
cydD
Glutathione/cysteine abc transporter export permease/atpase; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system
     
 0.576
yecD
Isochorismatase family protein; Belongs to the isochorismatase family
      
 0.561
proQ
Rna chaperone, putative prop translation regulator; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism
  
   
 0.542
modF
Molybdate transport system atp-binding protein; Probably not involved in the transport of molybdenum into the cell
  
  
  0.466
osmF
Glycine betaine abc transporter periplasmic binding protein osmf; Part of an ABC transporter complex involved in low-affinity glycine betaine uptake. Binds glycine betaine with low affinity
     
 0.444
cydC
Glutathione/cysteine abc transporter export permease/atpase; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system
  
  
  0.436
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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