STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ygbEInner membrane protein YgbE; Putative cytochrome oxidase subunit (107 aa)    
Predicted Functional Partners:
cysN
Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity
  
  
 0.816
cysC
Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate
  
  
 0.801
cysD
Sulfate adenylyltransferase subunit 2; Belongs to the PAPS reductase family. CysD subfamily
  
  
 0.786
yeiW
annotation not available
      
 0.784
mzrA
Modulator of envz/ompr regulon; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. Links the two-component systems CpxA/CpxR and EnvZ/OmpR
  
     0.777
yebO
annotation not available
  
     0.769
ybjO
annotation not available
  
     0.767
yjgN
annotation not available
      
 0.763
yhcN
annotation not available
  
     0.737
ampE
Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams
  
     0.732
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.