STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ygcSInner membrane metabolite transport protein YgcS; Putative transport protein (445 aa)    
Predicted Functional Partners:
ygcR
May play a role in a redox process
 
   
 0.963
ygcQ
May play a role in a redox process
       0.845
ydeE
A transporter able to export peptides. When overexpressed, allows cells deleted for multiple peptidases (pepA, pepB, pepD and pepN) to grow in the presence of dipeptides Ala-Gln or Gly-Tyr which otherwise inhibit growth . Cells overexpressing this protein have decreased intracellular levels of Ala-Gln dipeptide, and in a system that produces the Ala-Gln dipeptide overproduction of this protein increases export of the dipeptide .
    
 
 0.801
ygcU
Belongs to the FAD-binding oxidoreductase/transferase type 4 family
 
 
   0.783
ycaD
Uncharacterized MFS-type transporter YcaD; Putative transport; Not classified
      
 0.734
yqcE
Inner membrane protein YqcE; Putative transport protein
 
 
   0.678
setC
Involved in the efflux of sugars. The physiological role may be the detoxification of non-metabolizable sugar analogs
    
 
 0.629
yajR
Inner membrane transport protein YajR; Putative transport protein; Protein involved in response to drug
    
 
 0.622
ydeA
Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites. Transports L-arabinose and to a lesser extent IPTG. Seems to contribute to the control of the arabinose regulon
    
 
 0.599
kgtP
Uptake of alpha-ketoglutarate across the boundary membrane with the concomitant import of a cation (symport system).
  
   
 0.596
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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