STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yqcEPutative MFS transporter, inner membrane protein; Putative transport protein. (425 aa)    
Predicted Functional Partners:
yijD
DUF1422 family inner membrane protein.
      
 0.875
ygcE
Putative kinase; Belongs to the FGGY kinase family.
 
    0.856
uacT
Uric acid permease; Proton-dependent high-capacity transporter for uric acid. Shows also a low capacity for transport of xanthine at 37 degrees Celsius but not at 25 degrees Celsius; Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily.
   
  
 0.805
frvR
Putative frv operon regulator; Could be involved in the regulation of the transcription of the FRV operon.
  
     0.766
waaL
O-antigen ligase; Adds the O-antigen on the glucose group of LPS.
  
     0.704
waaU
Lipopolysaccharide core biosynthesis; Adds the terminal N-acetyl-D-glucosamine group on the glucose(II) group of LPS.
  
     0.673
ygcU
Putative FAD-linked oxidoreductase; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
 
     0.647
ycjN
Putative ABC sugar transporter periplasmic binding protein; Probably part of the binding-protein-dependent transport system YcjNOP; Belongs to the bacterial solute-binding protein 1 family.
  
    0.636
ycjQ
Putative Zn-dependent NAD(P)-binding oxidoreductase; Catalyzes the NAD(+)-dependent oxidation of the hydroxyl group at C3 of D-gulosides leading to 3-dehydro-D-gulosides. Probably functions in a metabolic pathway that transforms D-gulosides to D- glucosides. Is also able to catalyze the reverse reactions, i.e. the NADH-dependent reduction of the oxo group at C3 of 3-dehydro-D- gulosides leading to D-gulosides. In vitro, can oxidize D-gulose and methyl beta-D-guloside, and reduce methyl alpha-3-dehydro-D-guloside and methyl beta-3-dehydro-D-guloside. However, the actual specific physiol [...]
  
     0.579
ycjR
Putative TIM alpha/beta barrel enzyme; Catalyzes the epimerization at C4 of 3-dehydro-D-gulosides leading to 3-dehydro-D-glucosides. Probably functions in a metabolic pathway that transforms D-gulosides to D-glucosides. Can use methyl alpha-3-dehydro-D-glucoside and methyl beta-3-dehydro-D-glucoside as substrates in vitro. However, the actual specific physiological substrates for this metabolic pathway are unknown. Cannot act on D- psicose, D-fructose, D-tagatose, D-sorbose, L-xylulose, or L-ribulose. Belongs to the hyi family.
  
    0.573
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.