node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apaH | yqcC | b0049 | b2792 | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | DUF446 family protein; To the N-terminal of E.carotovora exoenzyme regulation regulon ORF1. The C-terminal part is colinear with YqcB. | 0.486 |
nfuA | rmf | b3414 | b0953 | Fe/S biogenesis protein, putative scaffold/chaperone protein; Involved in iron-sulfur cluster biogenesis under severe conditions such as iron starvation or oxidative stress. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. Required for E.coli to sustain oxidative stress and iron starvation. Also necessary for the use of extracellular DNA as the sole source of carbon and energy. Belongs to the NfuA family. | Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an immature dimeric form (90S ribosomes) which are converted to inactive 100S ribosomes (a process called ribosomal hibernation) by the hibernation promoting factor HPF. Inactivates ribosomes by covering the peptidyl transferase (PTase) center of the 23S rRNA and the entrance of peptide exit tunnel. However crystallization with T.thermophilus 70S ribosomes shows it binds near the 3'-end of the 16S rRNA near the anti-Shine-Dalgarno sequence, where it would sterically hinder translation inititation. In this cr [...] | 0.441 |
nfuA | yqcC | b3414 | b2792 | Fe/S biogenesis protein, putative scaffold/chaperone protein; Involved in iron-sulfur cluster biogenesis under severe conditions such as iron starvation or oxidative stress. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. Required for E.coli to sustain oxidative stress and iron starvation. Also necessary for the use of extracellular DNA as the sole source of carbon and energy. Belongs to the NfuA family. | DUF446 family protein; To the N-terminal of E.carotovora exoenzyme regulation regulon ORF1. The C-terminal part is colinear with YqcB. | 0.480 |
rdgC | yqcC | b0393 | b2792 | Recombination-associated protein RdgC; May be involved in recombination; Belongs to the RdgC family. | DUF446 family protein; To the N-terminal of E.carotovora exoenzyme regulation regulon ORF1. The C-terminal part is colinear with YqcB. | 0.603 |
rmf | nfuA | b0953 | b3414 | Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an immature dimeric form (90S ribosomes) which are converted to inactive 100S ribosomes (a process called ribosomal hibernation) by the hibernation promoting factor HPF. Inactivates ribosomes by covering the peptidyl transferase (PTase) center of the 23S rRNA and the entrance of peptide exit tunnel. However crystallization with T.thermophilus 70S ribosomes shows it binds near the 3'-end of the 16S rRNA near the anti-Shine-Dalgarno sequence, where it would sterically hinder translation inititation. In this cr [...] | Fe/S biogenesis protein, putative scaffold/chaperone protein; Involved in iron-sulfur cluster biogenesis under severe conditions such as iron starvation or oxidative stress. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. Required for E.coli to sustain oxidative stress and iron starvation. Also necessary for the use of extracellular DNA as the sole source of carbon and energy. Belongs to the NfuA family. | 0.441 |
rmf | yqcC | b0953 | b2792 | Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an immature dimeric form (90S ribosomes) which are converted to inactive 100S ribosomes (a process called ribosomal hibernation) by the hibernation promoting factor HPF. Inactivates ribosomes by covering the peptidyl transferase (PTase) center of the 23S rRNA and the entrance of peptide exit tunnel. However crystallization with T.thermophilus 70S ribosomes shows it binds near the 3'-end of the 16S rRNA near the anti-Shine-Dalgarno sequence, where it would sterically hinder translation inititation. In this cr [...] | DUF446 family protein; To the N-terminal of E.carotovora exoenzyme regulation regulon ORF1. The C-terminal part is colinear with YqcB. | 0.692 |
syd | truC | b2793 | b2791 | SecY-interacting protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function; Belongs to the Syd family. | tRNA(Ile1,Asp) pseudouridine(65) synthase; Responsible for synthesis of pseudouridine from uracil-65 in transfer RNAs; Belongs to the pseudouridine synthase RluA family. | 0.652 |
syd | yqcA | b2793 | b2790 | SecY-interacting protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function; Belongs to the Syd family. | Short-chain flavodoxin, FMN-binding; Probable electron transporter; Belongs to the flavodoxin family. MioC subfamily. | 0.652 |
syd | yqcC | b2793 | b2792 | SecY-interacting protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function; Belongs to the Syd family. | DUF446 family protein; To the N-terminal of E.carotovora exoenzyme regulation regulon ORF1. The C-terminal part is colinear with YqcB. | 0.651 |
truC | syd | b2791 | b2793 | tRNA(Ile1,Asp) pseudouridine(65) synthase; Responsible for synthesis of pseudouridine from uracil-65 in transfer RNAs; Belongs to the pseudouridine synthase RluA family. | SecY-interacting protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function; Belongs to the Syd family. | 0.652 |
truC | yqcA | b2791 | b2790 | tRNA(Ile1,Asp) pseudouridine(65) synthase; Responsible for synthesis of pseudouridine from uracil-65 in transfer RNAs; Belongs to the pseudouridine synthase RluA family. | Short-chain flavodoxin, FMN-binding; Probable electron transporter; Belongs to the flavodoxin family. MioC subfamily. | 0.903 |
truC | yqcC | b2791 | b2792 | tRNA(Ile1,Asp) pseudouridine(65) synthase; Responsible for synthesis of pseudouridine from uracil-65 in transfer RNAs; Belongs to the pseudouridine synthase RluA family. | DUF446 family protein; To the N-terminal of E.carotovora exoenzyme regulation regulon ORF1. The C-terminal part is colinear with YqcB. | 0.990 |
yciH | yqcC | b1282 | b2792 | Initiation factor function partial mimic, SUI1 family; Belongs to the SUI1 family. | DUF446 family protein; To the N-terminal of E.carotovora exoenzyme regulation regulon ORF1. The C-terminal part is colinear with YqcB. | 0.510 |
yejH | yqcC | b2184 | b2792 | Putative ATP-dependent DNA or RNA helicase; RadD contains helicase motifs, suggesting it may be a helicase, although that activity has not been observed (Probable). In combination with RadA is important in repair of double-strand DNA breaks (DSB). Has DNA-independent ATPase activity that is stimulated by single-stranded DNA-binding protein SSB. ATPase is stimulated by a peptide with the last 10 residues of SSB, but not when the peptide's last Phe residue is missing. Binds ssDNA; binding is slightly better in the presence of nucleotides. May be involved in resolution of branched DNA int [...] | DUF446 family protein; To the N-terminal of E.carotovora exoenzyme regulation regulon ORF1. The C-terminal part is colinear with YqcB. | 0.551 |
yohC | yqcC | b2135 | b2792 | Yip1 family inner membrane protein. | DUF446 family protein; To the N-terminal of E.carotovora exoenzyme regulation regulon ORF1. The C-terminal part is colinear with YqcB. | 0.582 |
yqcA | syd | b2790 | b2793 | Short-chain flavodoxin, FMN-binding; Probable electron transporter; Belongs to the flavodoxin family. MioC subfamily. | SecY-interacting protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function; Belongs to the Syd family. | 0.652 |
yqcA | truC | b2790 | b2791 | Short-chain flavodoxin, FMN-binding; Probable electron transporter; Belongs to the flavodoxin family. MioC subfamily. | tRNA(Ile1,Asp) pseudouridine(65) synthase; Responsible for synthesis of pseudouridine from uracil-65 in transfer RNAs; Belongs to the pseudouridine synthase RluA family. | 0.903 |
yqcA | yqcC | b2790 | b2792 | Short-chain flavodoxin, FMN-binding; Probable electron transporter; Belongs to the flavodoxin family. MioC subfamily. | DUF446 family protein; To the N-terminal of E.carotovora exoenzyme regulation regulon ORF1. The C-terminal part is colinear with YqcB. | 0.921 |
yqcC | apaH | b2792 | b0049 | DUF446 family protein; To the N-terminal of E.carotovora exoenzyme regulation regulon ORF1. The C-terminal part is colinear with YqcB. | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.486 |
yqcC | nfuA | b2792 | b3414 | DUF446 family protein; To the N-terminal of E.carotovora exoenzyme regulation regulon ORF1. The C-terminal part is colinear with YqcB. | Fe/S biogenesis protein, putative scaffold/chaperone protein; Involved in iron-sulfur cluster biogenesis under severe conditions such as iron starvation or oxidative stress. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. Required for E.coli to sustain oxidative stress and iron starvation. Also necessary for the use of extracellular DNA as the sole source of carbon and energy. Belongs to the NfuA family. | 0.480 |