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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fucPMfs transporter, fhs family, l-fucose permease; Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-rhamnose and L-arabinose (438 aa)    
Predicted Functional Partners:
fucI
L-fucose/d-arabinose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose. Is also able to convert D-arabinose into D-ribulose, but this isomerase has a higher affinity for fucose and fuculose than for arabinose and ribulose, respectively
 
 
 0.946
glpT
Mfs transporter, opa family, glycerol-3-phosphate transporter; Responsible for glycerol-3-phosphate uptake
   
  
 0.903
xylE
Mfs transporter, sp family, xylose:h+ symportor; Uptake of D-xylose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Glucose is not transported, but can compete for xylose binding sites and can inhibit xylose transport (in vitro)
 
   
 0.895
lacY
Mfs transporter, ohs family, lactose permease; Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). Can transport lactose, melibiose, lactulose or the analog methyl-1-thio-beta,D- galactopyranoside (TMG), but not sucrose or fructose The substrate specificity is directed toward the galactopyranosyl moiety of the substrate
     
 0.889
yajR
Inner membrane transport protein YajR; Putative transport protein; Protein involved in response to drug
      
 0.889
fucR
Deor family transcriptional regulator, l-fucose operon activator; Transcriptional activator of the fuc operon
 
 
 
 0.883
fucK
L-fuculokinase; Catalyzes the phosphorylation of L-fuculose. Can also phosphorylate, with lower efficiency, D-ribulose, D-xylulose and D- fructose
 
  
 0.876
emrD
Mfs transporter, dha1 family, 2-module integral membrane pump emrd; Multidrug resistance pump that participates in a low energy shock adaptive response
      
 0.872
fucA
L-fuculose-1-phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose . Catalyzes the reversible cleavage of L-fuculose 1- phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L- lactaldehyde Ref.8, Ref.9, Also able to catalyze the reversible cleavage of D- ribulose 1-phosphate, but FucA has a higher affinity for L-fuculose 1- phosphate and L-lactaldehyde than for D-ribulose 1-phosphate and glycolaldehyde, respectively . FucA possesses a high specificity for the dihydroxyacetone phosphate (DHAP), but accepts a great variety of different aldehydes and has [...]
 
  
 0.859
uxaA
D-altronate dehydratase; Catalyzes the dehydration of D-altronate
  
  
 0.834
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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